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Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma.
Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17037-42. doi: 10.1073/pnas.0902880106. Epub 2009 Sep 23.
Proc Natl Acad Sci U S A. 2009.
PMID: 19805107
Free PMC article.
Jak2 tyrosine kinase and cancer: how good cells get HiJAKed.
Godeny MD, Sayeski PP.
Godeny MD, et al.
Anticancer Agents Med Chem. 2007 Nov;7(6):643-50. doi: 10.2174/187152007782330105.
Anticancer Agents Med Chem. 2007.
PMID: 18045059
Review.
Item in Clipboard
The N-terminal SH2 domain of the tyrosine phosphatase, SHP-2, is essential for Jak2-dependent signaling via the angiotensin II type AT1 receptor.
Godeny MD, Sayyah J, VonDerLinden D, Johns M, Ostrov DA, Caldwell-Busby J, Sayeski PP.
Godeny MD, et al.
Cell Signal. 2007 Mar;19(3):600-9. doi: 10.1016/j.cellsig.2006.08.010. Epub 2006 Sep 1.
Cell Signal. 2007.
PMID: 17027227
Item in Clipboard
ANG II-induced cell proliferation is dually mediated by c-Src/Yes/Fyn-regulated ERK1/2 activation in the cytoplasm and PKCzeta-controlled ERK1/2 activity within the nucleus.
Godeny MD, Sayeski PP.
Godeny MD, et al.
Am J Physiol Cell Physiol. 2006 Dec;291(6):C1297-307. doi: 10.1152/ajpcell.00617.2005. Epub 2006 May 24.
Am J Physiol Cell Physiol. 2006.
PMID: 16723512
Free article.
Item in Clipboard
ERK1/2 regulates ANG II-dependent cell proliferation via cytoplasmic activation of RSK2 and nuclear activation of elk1.
Godeny MD, Sayeski PP.
Godeny MD, et al.
Am J Physiol Cell Physiol. 2006 Dec;291(6):C1308-17. doi: 10.1152/ajpcell.00618.2005. Epub 2006 May 24.
Am J Physiol Cell Physiol. 2006.
PMID: 16723511
Free article.
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Jak2 tyrosine kinase: a true jak of all trades?
Sandberg EM, Wallace TA, Godeny MD, VonDerLinden D, Sayeski PP.
Sandberg EM, et al. Among authors: godeny md.
Cell Biochem Biophys. 2004;41(2):207-32. doi: 10.1385/cbb:41:2:207.
Cell Biochem Biophys. 2004.
PMID: 15475610
Review.
Item in Clipboard
Jak2 tyrosine kinase mediates angiotensin II-dependent inactivation of ERK2 via induction of mitogen-activated protein kinase phosphatase 1.
Sandberg EM, Ma X, VonDerLinden D, Godeny MD, Sayeski PP.
Sandberg EM, et al. Among authors: godeny md.
J Biol Chem. 2004 Jan 16;279(3):1956-67. doi: 10.1074/jbc.M303540200. Epub 2003 Oct 9.
J Biol Chem. 2004.
PMID: 14551204
Free article.
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