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85 results
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Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular location.
Goedhart J, van Unen J, Adjobo-Hermans MJ, Gadella TW Jr. Goedhart J, et al. Sci Rep. 2013;3:2284. doi: 10.1038/srep02284. Sci Rep. 2013. PMID: 23884432 Free PMC article.
Plant G protein heterotrimers require dual lipidation motifs of Galpha and Ggamma and do not dissociate upon activation.
Adjobo-Hermans MJ, Goedhart J, Gadella TW Jr. Adjobo-Hermans MJ, et al. Among authors: goedhart j. J Cell Sci. 2006 Dec 15;119(Pt 24):5087-97. doi: 10.1242/jcs.03284. J Cell Sci. 2006. PMID: 17158913
Combination of a spinning disc confocal unit with frequency-domain fluorescence lifetime imaging microscopy.
van Munster EB, Goedhart J, Kremers GJ, Manders EM, Gadella TW Jr. van Munster EB, et al. Among authors: goedhart j. Cytometry A. 2007 Apr;71(4):207-14. doi: 10.1002/cyto.a.20379. Cytometry A. 2007. PMID: 17266147
Improved green and blue fluorescent proteins for expression in bacteria and mammalian cells.
Kremers GJ, Goedhart J, van den Heuvel DJ, Gerritsen HC, Gadella TW Jr. Kremers GJ, et al. Among authors: goedhart j. Biochemistry. 2007 Mar 27;46(12):3775-83. doi: 10.1021/bi0622874. Epub 2007 Feb 27. Biochemistry. 2007. PMID: 17323929
Sensitive detection of p65 homodimers using red-shifted and fluorescent protein-based FRET couples.
Goedhart J, Vermeer JE, Adjobo-Hermans MJ, van Weeren L, Gadella TW Jr. Goedhart J, et al. PLoS One. 2007 Oct 10;2(10):e1011. doi: 10.1371/journal.pone.0001011. PLoS One. 2007. PMID: 17925859 Free PMC article.
Imaging phosphatidylinositol 4-phosphate dynamics in living plant cells.
Vermeer JE, Thole JM, Goedhart J, Nielsen E, Munnik T, Gadella TW Jr. Vermeer JE, et al. Among authors: goedhart j. Plant J. 2009 Jan;57(2):356-72. doi: 10.1111/j.1365-313X.2008.03679.x. Epub 2008 Oct 25. Plant J. 2009. PMID: 18785997
Regulation of PLCbeta1a membrane anchoring by its substrate phosphatidylinositol (4,5)-bisphosphate.
Adjobo-Hermans MJ, Goedhart J, Gadella TW Jr. Adjobo-Hermans MJ, et al. Among authors: goedhart j. J Cell Sci. 2008 Nov 15;121(Pt 22):3770-7. doi: 10.1242/jcs.029785. Epub 2008 Oct 28. J Cell Sci. 2008. PMID: 18957514
Bright cyan fluorescent protein variants identified by fluorescence lifetime screening.
Goedhart J, van Weeren L, Hink MA, Vischer NO, Jalink K, Gadella TW Jr. Goedhart J, et al. Nat Methods. 2010 Feb;7(2):137-9. doi: 10.1038/nmeth.1415. Epub 2010 Jan 17. Nat Methods. 2010. PMID: 20081836
Real-time visualization of heterotrimeric G protein Gq activation in living cells.
Adjobo-Hermans MJ, Goedhart J, van Weeren L, Nijmeijer S, Manders EM, Offermanns S, Gadella TW Jr. Adjobo-Hermans MJ, et al. Among authors: goedhart j. BMC Biol. 2011 May 27;9:32. doi: 10.1186/1741-7007-9-32. BMC Biol. 2011. PMID: 21619590 Free PMC article.
Quantitative co-expression of proteins at the single cell level--application to a multimeric FRET sensor.
Goedhart J, van Weeren L, Adjobo-Hermans MJ, Elzenaar I, Hink MA, Gadella TW Jr. Goedhart J, et al. PLoS One. 2011;6(11):e27321. doi: 10.1371/journal.pone.0027321. Epub 2011 Nov 17. PLoS One. 2011. PMID: 22114669 Free PMC article.
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