Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

2,574 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Curcumin as "Curecumin": from kitchen to clinic.
Goel A, Kunnumakkara AB, Aggarwal BB. Goel A, et al. Biochem Pharmacol. 2008 Feb 15;75(4):787-809. doi: 10.1016/j.bcp.2007.08.016. Epub 2007 Aug 19. Biochem Pharmacol. 2008. PMID: 17900536 Review.
Various preclinical cell culture and animal studies suggest that curcumin has potential as an antiproliferative, anti-invasive, and antiangiogenic agent; as a mediator of chemoresistance and radioresistance; as a chemopreventive agent; and as a therapeutic ag …
Various preclinical cell culture and animal studies suggest that curcumin has potential as an antiproliferative, anti-invasive, and antiangi …
Multi-targeted therapy by curcumin: how spicy is it?
Goel A, Jhurani S, Aggarwal BB. Goel A, et al. Mol Nutr Food Res. 2008 Sep;52(9):1010-30. doi: 10.1002/mnfr.200700354. Mol Nutr Food Res. 2008. PMID: 18384098 Review.
Curcumin, a yellow component of turmeric or curry powder, however, is an exception. Although inhibitors of cyclooxygenase-2, HER2, tumor necrosis factor, EGFR, Bcr-abl, proteosome, and vascular endothelial cell growth factor have been approved for human use by the United S …
Curcumin, a yellow component of turmeric or curry powder, however, is an exception. Although inhibitors of cyclooxygenase-2, HER2, tu …
Cancer chemoprevention by dietary polyphenols: promising role for epigenetics.
Link A, Balaguer F, Goel A. Link A, et al. Among authors: goel a. Biochem Pharmacol. 2010 Dec 15;80(12):1771-92. doi: 10.1016/j.bcp.2010.06.036. Epub 2010 Jun 26. Biochem Pharmacol. 2010. PMID: 20599773 Free PMC article. Review.
In this article, we first discuss the contribution of diet and environmental factors on epigenetic alterations; subsequently, we provide a comprehensive review of literature on the role of various dietary polyphenols. In particular, we summarize the current knowledge on …
In this article, we first discuss the contribution of diet and environmental factors on epigenetic alterations; subsequently, we provide …
Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs.
Goel A, Aggarwal BB. Goel A, et al. Nutr Cancer. 2010;62(7):919-30. doi: 10.1080/01635581.2010.509835. Nutr Cancer. 2010. PMID: 20924967 Review.
Curcumin (diferuloylmethane), the yellow pigment in Indian saffron (Curcuma longa; also called turmeric, haldi, or haridara in the East and curry powder in the West), has been consumed by people for centuries as a dietary component and for a variety of proinflammato …
Curcumin (diferuloylmethane), the yellow pigment in Indian saffron (Curcuma longa; also called turmeric, haldi, or haridara in the East and …
Epigenetic changes induced by curcumin and other natural compounds.
Reuter S, Gupta SC, Park B, Goel A, Aggarwal BB. Reuter S, et al. Among authors: goel a. Genes Nutr. 2011 May;6(2):93-108. doi: 10.1007/s12263-011-0222-1. Epub 2011 Apr 24. Genes Nutr. 2011. PMID: 21516481 Free PMC article.
Curcumin (diferuloylmethane), a component of the golden spice Curcuma longa, commonly known as turmeric, has recently been determined to induce epigenetic changes. ...The development of curcumin for clinical use as a regulator of epigenetic changes, however, needs f …
Curcumin (diferuloylmethane), a component of the golden spice Curcuma longa, commonly known as turmeric, has recently been determined …
Boswellic acid induces epigenetic alterations by modulating DNA methylation in colorectal cancer cells.
Shen Y, Takahashi M, Byun HM, Link A, Sharma N, Balaguer F, Leung HC, Boland CR, Goel A. Shen Y, et al. Among authors: goel a. Cancer Biol Ther. 2012 May;13(7):542-52. doi: 10.4161/cbt.19604. Epub 2012 May 1. Cancer Biol Ther. 2012. PMID: 22415137 Free PMC article.
Using genome-wide DNA methylation and gene expression microarray analyses, we discovered that AKBA induced a modest genome-wide demethylation that permitted simultaneous re-activation of the corresponding tumor suppressor genes. ...These results suggest that not only boswe …
Using genome-wide DNA methylation and gene expression microarray analyses, we discovered that AKBA induced a modest genome-wide demet …
Curcumin modulates DNA methylation in colorectal cancer cells.
Link A, Balaguer F, Shen Y, Lozano JJ, Leung HC, Boland CR, Goel A. Link A, et al. Among authors: goel a. PLoS One. 2013;8(2):e57709. doi: 10.1371/journal.pone.0057709. Epub 2013 Feb 27. PLoS One. 2013. PMID: 23460897 Free PMC article.
CONCLUSIONS: Our data provide previously unrecognized evidence for curcumin-mediated DNA methylation alterations as a potential mechanism of colon cancer chemoprevention. In contrast to non-specific global hypomethylation induced by 5-aza-CdR, curcumin-induced methylation …
CONCLUSIONS: Our data provide previously unrecognized evidence for curcumin-mediated DNA methylation alterations as a potential mecha …
Curcumin chemosensitizes 5-fluorouracil resistant MMR-deficient human colon cancer cells in high density cultures.
Shakibaei M, Buhrmann C, Kraehe P, Shayan P, Lueders C, Goel A. Shakibaei M, et al. Among authors: goel a. PLoS One. 2014 Jan 3;9(1):e85397. doi: 10.1371/journal.pone.0085397. eCollection 2014. PLoS One. 2014. PMID: 24404205 Free PMC article.
OBJECTIVE: Treatment of colorectal cancer (CRC) remains a clinical challenge, as more than 15% of patients are resistant to 5-Fluorouracil (5-FU)-based chemotherapeutic regimens, and tumor recurrence rates can be as high as 50-60%. ...These effects of curcumin in enhancing …
OBJECTIVE: Treatment of colorectal cancer (CRC) remains a clinical challenge, as more than 15% of patients are resistant to 5-Fluorou …
DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer.
Toiyama Y, Okugawa Y, Goel A. Toiyama Y, et al. Among authors: goel a. Biochem Biophys Res Commun. 2014 Dec 5;455(1-2):43-57. doi: 10.1016/j.bbrc.2014.08.001. Epub 2014 Aug 13. Biochem Biophys Res Commun. 2014. PMID: 25128828 Free PMC article. Review.
Recent advances in epigenetics have not only offered a deeper understanding of the underlying mechanism(s) of carcinogenesis, but have also allowed identification of clinically relevant putative biomarkers for the early detection, disease monitoring, prognosis and risk ass …
Recent advances in epigenetics have not only offered a deeper understanding of the underlying mechanism(s) of carcinogenesis, but hav …
Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT.
Buhrmann C, Kraehe P, Lueders C, Shayan P, Goel A, Shakibaei M. Buhrmann C, et al. Among authors: goel a. PLoS One. 2014 Sep 19;9(9):e107514. doi: 10.1371/journal.pone.0107514. eCollection 2014. PLoS One. 2014. PMID: 25238234 Free PMC article.
OBJECTIVE: Interaction of stromal and tumor cells plays a dynamic role in initiating and enhancing carcinogenesis. In this study, we investigated the crosstalk between colorectal cancer (CRC) cells with stromal fibroblasts and the anti-cancer effects of curcumin and 5-Fluo …
OBJECTIVE: Interaction of stromal and tumor cells plays a dynamic role in initiating and enhancing carcinogenesis. In this study, we …
2,574 results
Jump to page
Feedback