Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

42 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Interaction of G protein Gbetagamma dimers with small GTP-binding proteins of the Rho family.
Harhammer R, Gohla A, Schultz G. Harhammer R, et al. Among authors: gohla a. FEBS Lett. 1996 Dec 16;399(3):211-4. doi: 10.1016/s0014-5793(96)01327-0. FEBS Lett. 1996. PMID: 8985147
In addition, brain Gbetagamma, but not transducin Gbetagamma, was able to inhibit GTPgammaS binding to GST-Rho in a concentration-dependent manner. ...
In addition, brain Gbetagamma, but not transducin Gbetagamma, was able to inhibit GTPgammaS binding to GST-Rho in a concentration-dep …
An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver.
Gohla A, Klement K, Piekorz RP, Pexa K, vom Dahl S, Spicher K, Dreval V, Häussinger D, Birnbaumer L, Nürnberg B. Gohla A, et al. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):3003-8. doi: 10.1073/pnas.0611434104. Epub 2007 Feb 12. Proc Natl Acad Sci U S A. 2007. PMID: 17296938 Free PMC article.
The presence of a single active allele of Galpha(i3) is sufficient for embryonic development, whereas at least one allele of Galpha(i2) is required for extrauterine life. ...
The presence of a single active allele of Galpha(i3) is sufficient for embryonic development, whereas at least one allele of Galpha(i …
The heterotrimeric G protein G(i3) regulates hepatic autophagy downstream of the insulin receptor.
Gohla A, Klement K, Nürnberg B. Gohla A, et al. Autophagy. 2007 Jul-Aug;3(4):393-5. doi: 10.4161/auto.4256. Epub 2007 Jul 10. Autophagy. 2007. PMID: 17457037
This points to a previously unrecognized cross talk between the insulin receptor tyrosine kinase and G(i3). Interestingly, G(i3) is localized not only to plasma membranes but also to membranes of the autophagosomal compartment. ...Here, we discuss recent findings and propo …
This points to a previously unrecognized cross talk between the insulin receptor tyrosine kinase and G(i3). Interestingly, G(i3) is l …
Pleiotropic effects of Pasteurella multocida toxin are mediated by Gq-dependent and -independent mechanisms. involvement of Gq but not G11.
Zywietz A, Gohla A, Schmelz M, Schultz G, Offermanns S. Zywietz A, et al. Among authors: gohla a. J Biol Chem. 2001 Feb 9;276(6):3840-5. doi: 10.1074/jbc.M007819200. Epub 2000 Nov 2. J Biol Chem. 2001. PMID: 11062245
Pasteurella multocida toxin (PMT) is a highly potent mitogen for a variety of cell types. PMT has been shown to induce various cellular signaling processes, and it has been suggested to function through the heterotrimeric G-proteins G(q)/G(11). ...These data show th …
Pasteurella multocida toxin (PMT) is a highly potent mitogen for a variety of cell types. PMT has been shown to induce various …
The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins.
Wittau N, Grosse R, Kalkbrenner F, Gohla A, Schultz G, Gudermann T. Wittau N, et al. Among authors: gohla a. Oncogene. 2000 Aug 31;19(37):4199-209. doi: 10.1038/sj.onc.1203777. Oncogene. 2000. PMID: 10980593
A rise of the intracellular calcium concentration was necessary and sufficient to mediate galanin-induced ERK activation. In support of G(i) coupling, stimulation of GALR2 expressed in HEK293 cells inhibited isoproterenol-induced cAMP accumulation and raised cAMP levels in
A rise of the intracellular calcium concentration was necessary and sufficient to mediate galanin-induced ERK activation. In support
Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction.
Gohla A, Schultz G, Offermanns S. Gohla A, et al. Circ Res. 2000 Aug 4;87(3):221-7. doi: 10.1161/01.res.87.3.221. Circ Res. 2000. PMID: 10926873
Receptors of various vasocontractors were found to couple to G(q)/G(11) and G(12)/G(13), and constitutively active forms of G alpha(12) and G alpha(13) induced a pronounced contraction of vascular smooth muscle cells that could be blocked by C3 exoenzyme, by inhibition of …
Receptors of various vasocontractors were found to couple to G(q)/G(11) and G(12)/G(13), and constitutively active forms of G alpha(12) and …
Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation.
Gohla A, Offermanns S, Wilkie TM, Schultz G. Gohla A, et al. J Biol Chem. 1999 Jun 18;274(25):17901-7. doi: 10.1074/jbc.274.25.17901. J Biol Chem. 1999. PMID: 10364236
Rho stimulation leads to a rapid remodeling of the actin cytoskeleton and subsequent stress fiber formation. We investigated the involvement of G12 or G13 in stress fiber formation induced through a variety of Gq/G11-coupled receptors. ...Our data demonstrate that m …
Rho stimulation leads to a rapid remodeling of the actin cytoskeleton and subsequent stress fiber formation. We investigated the invo …
The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho.
Gohla A, Harhammer R, Schultz G. Gohla A, et al. J Biol Chem. 1998 Feb 20;273(8):4653-9. doi: 10.1074/jbc.273.8.4653. J Biol Chem. 1998. PMID: 9468525
Lysophosphatidic acid (LPA) utilizes a G-protein-coupled receptor to activate the small GTP-binding protein Rho and to induce rapid remodeling of the actin cytoskeleton. ...In Swiss 3T3 cells, incubation with LPA or microinjection of constitutively active mutants of Galpha …
Lysophosphatidic acid (LPA) utilizes a G-protein-coupled receptor to activate the small GTP-binding protein Rho and to induce rapid r …
Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice.
Offermanns S, Zhao LP, Gohla A, Sarosi I, Simon MI, Wilkie TM. Offermanns S, et al. Among authors: gohla a. EMBO J. 1998 Aug 3;17(15):4304-12. doi: 10.1093/emboj/17.15.4304. EMBO J. 1998. PMID: 9687499 Free PMC article.
These mutants showed a high incidence of cardiac malformation. In addition, G alpha q(-/-);G alpha 11(-/+) newborns suffered from craniofacial defects. ...These data demonstrate overlap in G alpha q and G alpha 11 gene functions and indicate that the Gq class of G proteins …
These mutants showed a high incidence of cardiac malformation. In addition, G alpha q(-/-);G alpha 11(-/+) newborns suffered from cra …
Human HAD phosphatases: structure, mechanism, and roles in health and disease.
Seifried A, Schultz J, Gohla A. Seifried A, et al. Among authors: gohla a. FEBS J. 2013 Jan;280(2):549-71. doi: 10.1111/j.1742-4658.2012.08633.x. Epub 2012 Jun 13. FEBS J. 2013. PMID: 22607316 Review.
While the overall sequence similarity between HAD phosphatases is generally very low, family members can be identified based on the presence of a characteristic Rossmann-like fold and the active site sequence DxDx(V/T). HAD phosphatases employ an aspartate residue as a
While the overall sequence similarity between HAD phosphatases is generally very low, family members can be identified based on the presence …
42 results
Jump to page
Feedback