Gokulan K - Search Results

1

Crystal structure of Mycobacterium tuberculosis diaminopimelate decarboxylase, an essential enzyme in bacterial lysine biosynthesis.

Gokulan K, Rupp B, Pavelka MS Jr, Jacobs WR Jr, Sacchettini JC. Gokulan K, et al. J Biol Chem. 2003 May 16;278(20):18588-96. doi: 10.1074/jbc.M301549200. Epub 2003 Mar 10. J Biol Chem. 2003. PMID: 12637582 Free article.

2

Crystal structure of Mycobacterium tuberculosis LrpA, a leucine-responsive global regulator associated with starvation response.

Reddy MC, Gokulan K, Jacobs WR Jr, Ioerger TR, Sacchettini JC. Reddy MC, et al. Among authors: gokulan k. Protein Sci. 2008 Jan;17(1):159-70. doi: 10.1110/ps.073192208. Epub 2007 Nov 27. Protein Sci. 2008. PMID: 18042675 Free PMC article.

3

Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.

Gokulan K, O'Leary SE, Russell WK, Russell DH, Lalgondar M, Begley TP, Ioerger TR, Sacchettini JC. Gokulan K, et al. J Biol Chem. 2013 Jun 7;288(23):16484-16494. doi: 10.1074/jbc.M113.468892. Epub 2013 Apr 24. J Biol Chem. 2013. PMID: 23615910 Free PMC article.

4

Cocrystal structures of NC6.8 Fab identify key interactions for high potency sweetener recognition: implications for the design of synthetic sweeteners.

Gokulan K, Khare S, Ronning DR, Linthicum SD, Sacchettini JC, Rupp B. Gokulan K, et al. Biochemistry. 2005 Jul 26;44(29):9889-98. doi: 10.1021/bi050613u. Biochemistry. 2005. PMID: 16026161

5

Mechanistic and structural studies of H373Q flavocytochrome b2: effects of mutating the active site base.

Tsai CL, Gokulan K, Sobrado P, Sacchettini JC, Fitzpatrick PF. Tsai CL, et al. Among authors: gokulan k. Biochemistry. 2007 Jul 3;46(26):7844-51. doi: 10.1021/bi7005543. Epub 2007 Jun 12. Biochemistry. 2007. PMID: 17563122 Free PMC article.

6

Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations.

Gokulan K, Aggarwal A, Shipman L, Besra GS, Sacchettini JC. Gokulan K, et al. Acta Crystallogr D Biol Crystallogr. 2011 Jul;67(Pt 7):657-69. doi: 10.1107/S0907444911020221. Epub 2011 Jun 11. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21697604 Free PMC article.

7

Charged residue changes in the carboxy-terminus of alpha-tropomyosin alter mouse cardiac muscle contractility.

Gaffin RD, Gokulan K, Sacchettini JC, Hewett T, Klevitsky R, Robbins J, Muthuchamy M. Gaffin RD, et al. Among authors: gokulan k. J Physiol. 2004 Apr 15;556(Pt 2):531-43. doi: 10.1113/jphysiol.2003.058487. Epub 2004 Feb 6. J Physiol. 2004. PMID: 14766940 Free PMC article.

8

Asp79 makes a large, unfavorable contribution to the stability of RNase Sa.

Trevino SR, Gokulan K, Newsom S, Thurlkill RL, Shaw KL, Mitkevich VA, Makarov AA, Sacchettini JC, Scholtz JM, Pace CN. Trevino SR, et al. Among authors: gokulan k. J Mol Biol. 2005 Dec 9;354(4):967-78. doi: 10.1016/j.jmb.2005.09.091. Epub 2005 Oct 21. J Mol Biol. 2005. PMID: 16288913

9

KasA, another brick in the mycobacterial cell wall.

Swanson S, Gokulan K, Sacchettini JC. Swanson S, et al. Among authors: gokulan k. Structure. 2009 Jul 15;17(7):914-5. doi: 10.1016/j.str.2009.06.006. Structure. 2009. PMID: 19604470 Free article. No abstract available.

10

Changes in end-to-end interactions of tropomyosin affect mouse cardiac muscle dynamics.

Gaffin RD, Gokulan K, Sacchettini JC, Hewett TE, Klevitsky R, Robbins J, Sarin V, Zawieja DC, Meininger GA, Muthuchamy M. Gaffin RD, et al. Among authors: gokulan k. Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H552-63. doi: 10.1152/ajpheart.00688.2005. Epub 2006 Feb 24. Am J Physiol Heart Circ Physiol. 2006. PMID: 16501024 Free article.

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