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An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome.
Canna SW, de Jesus AA, Gouni S, Brooks SR, Marrero B, Liu Y, DiMattia MA, Zaal KJ, Sanchez GA, Kim H, Chapelle D, Plass N, Huang Y, Villarino AV, Biancotto A, Fleisher TA, Duncan JA, O'Shea JJ, Benseler S, Grom A, Deng Z, Laxer RM, Goldbach-Mansky R. Canna SW, et al. Nat Genet. 2014 Oct;46(10):1140-6. doi: 10.1038/ng.3089. Epub 2014 Sep 14. Nat Genet. 2014. PMID: 25217959 Free PMC article.
IL-1 blockade in autoinflammatory syndromes.
Jesus AA, Goldbach-Mansky R. Jesus AA, et al. Annu Rev Med. 2014;65:223-44. doi: 10.1146/annurev-med-061512-150641. Annu Rev Med. 2014. PMID: 24422572 Free PMC article. Review.
179 results