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65 results
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Plant lectin can target receptors containing sialic acid, exemplified by podoplanin, to inhibit transformed cell growth and migration.
Ochoa-Alvarez JA, Krishnan H, Shen Y, Acharya NK, Han M, McNulty DE, Hasegawa H, Hyodo T, Senga T, Geng JG, Kosciuk M, Shin SS, Goydos JS, Temiakov D, Nagele RG, Goldberg GS. Ochoa-Alvarez JA, et al. Among authors: goldberg gs. PLoS One. 2012;7(7):e41845. doi: 10.1371/journal.pone.0041845. Epub 2012 Jul 23. PLoS One. 2012. PMID: 22844530 Free PMC article.
Serines in the intracellular tail of podoplanin (PDPN) regulate cell motility.
Krishnan H, Ochoa-Alvarez JA, Shen Y, Nevel E, Lakshminarayanan M, Williams MC, Ramirez MI, Miller WT, Goldberg GS. Krishnan H, et al. Among authors: goldberg gs. J Biol Chem. 2013 Apr 26;288(17):12215-21. doi: 10.1074/jbc.C112.446823. Epub 2013 Mar 25. J Biol Chem. 2013. PMID: 23530051 Free PMC article.
Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms.
Ochoa-Alvarez JA, Krishnan H, Pastorino JG, Nevel E, Kephart D, Lee JJ, Retzbach EP, Shen Y, Fatahzadeh M, Baredes S, Kalyoussef E, Honma M, Adelson ME, Kaneko MK, Kato Y, Young MA, Deluca-Rapone L, Shienbaum AJ, Yin K, Jensen LD, Goldberg GS. Ochoa-Alvarez JA, et al. Among authors: goldberg gs. Oncotarget. 2015 Apr 20;6(11):9045-60. doi: 10.18632/oncotarget.3515. Oncotarget. 2015. PMID: 25826087 Free PMC article.
Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.
Nahta R, Al-Mulla F, Al-Temaimi R, Amedei A, Andrade-Vieira R, Bay SN, Brown DG, Calaf GM, Castellino RC, Cohen-Solal KA, Colacci A, Cruickshanks N, Dent P, Di Fiore R, Forte S, Goldberg GS, Hamid RA, Krishnan H, Laird DW, Lasfar A, Marignani PA, Memeo L, Mondello C, Naus CC, Ponce-Cusi R, Raju J, Roy D, Roy R, Ryan EP, Salem HK, Scovassi AI, Singh N, Vaccari M, Vento R, Vondráček J, Wade M, Woodrick J, Bisson WH. Nahta R, et al. Among authors: goldberg gs. Carcinogenesis. 2015 Jun;36 Suppl 1(Suppl 1):S2-18. doi: 10.1093/carcin/bgv028. Carcinogenesis. 2015. PMID: 26106139 Free PMC article. Review.
Podoplanin: An emerging cancer biomarker and therapeutic target.
Krishnan H, Rayes J, Miyashita T, Ishii G, Retzbach EP, Sheehan SA, Takemoto A, Chang YW, Yoneda K, Asai J, Jensen L, Chalise L, Natsume A, Goldberg GS. Krishnan H, et al. Among authors: goldberg gs. Cancer Sci. 2018 May;109(5):1292-1299. doi: 10.1111/cas.13580. Cancer Sci. 2018. PMID: 29575529 Free PMC article. Review.
65 results