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History about the discovery of the renin-angiotensin system.
Basso N, Terragno NA. Basso N, et al. Hypertension. 2001 Dec 1;38(6):1246-9. doi: 10.1161/hy1201.101214. Hypertension. 2001. PMID: 11751697
The history of the discovery of the renin-angiotensin system began in 1898 with the studies made by Tigerstedt and Bergman, who reported the pressor effect of renal extracts; they named the renal substance renin based on its origin. In 1934, Harry Goldblat …
The history of the discovery of the renin-angiotensin system began in 1898 with the studies made by Tigerstedt and Bergman, wh …
[Historical Archives of Italian Nephrology. Goldblatt, kidney and hypertension: three steps in the history of nephrology].
Timio M. Timio M. G Ital Nefrol. 2003 Sep-Oct;20(5):512-5. G Ital Nefrol. 2003. PMID: 14634967 Italian.
Tigersted and Bergman showed that renin was the missing link. Renal ischemia as cause of hypertension in dogs opened a new chapter in the connection between kidney circulation and blood pressure elevation. ...Goldblatt's lasting ideas are more t …
Tigersted and Bergman showed that renin was the missing link. Renal ischemia as cause of hypertension in dogs opened a new cha …
["Goldblatt phenomenon of the uterus" and latent kidney disease as the cause of pregnancy-induced hypertension--epidemiology and therapeutic consequences].
Künzel W. Künzel W. Geburtshilfe Frauenheilkd. 1990 Nov;50(11):833-41. doi: 10.1055/s-2008-1026377. Geburtshilfe Frauenheilkd. 1990. PMID: 2283006 Review. German.
The aetiology of pregnancy-induced hypertension (PIH) is at present unknown. Epidemiological data lead us to assume, that two main mechanisms could be responsible for the development of PIH. They are not well understood in their complexity, but result in the same pattern o …
The aetiology of pregnancy-induced hypertension (PIH) is at present unknown. Epidemiological data lead us to assume, that two main me …
Harry Goldblatt and the discovery of renin.
Van Epps HL. Van Epps HL. J Exp Med. 2005 May 2;201(9):1351. doi: 10.1084/jem.2019fta. J Exp Med. 2005. PMID: 15940810 Free PMC article.
In 1934, pathologist Harry Goldblatt established the first animal model of hypertension. This model provided researchers with the tools to delineate the renin-angiotensin system of blood pressure control and, eventually, to design enzyme inhibitors for the tr …
In 1934, pathologist Harry Goldblatt established the first animal model of hypertension. This model provided researchers with …
Hypertension and atherosclerosis in cholesterol-fed rabbits. Part 1. Mild, two-kidney, one-clip Goldblatt hypertension treated with enalapril.
Overturf M, Sybers H, Schaper J, Taegtmeyer H. Overturf M, et al. Atherosclerosis. 1986 Mar;59(3):283-99. doi: 10.1016/0021-9150(86)90124-3. Atherosclerosis. 1986. PMID: 3008772
Ten groups of New Zealand white rabbits were used to study the effects of mild, chronic two-kidney, one-clip hypertension (HT) and long-term antihypertensive therapy on atherogenesis. Five groups were fed a normal diet (ND) over the 8-month study period; 2 groups, o …
Ten groups of New Zealand white rabbits were used to study the effects of mild, chronic two-kidney, one-clip hypertension (HT) …
A cornerstone in the history of hypertension: the seventieth anniversary of the discovery of angiotensin.
Milei J. Milei J. J Cardiovasc Med (Hagerstown). 2010 Apr;11(4):260-4. doi: 10.2459/JCM.0b013e3283356607. J Cardiovasc Med (Hagerstown). 2010. PMID: 19956076
In 1939, two independent teams, in Buenos Aires and Indianapolis, identified the polypeptide angiotensin. In 1934, Goldblatt et al. demonstrated that partial occlusion of the renal arteries produces hypertension in dogs, and Houssay in 1936 predicted the presence of …
In 1939, two independent teams, in Buenos Aires and Indianapolis, identified the polypeptide angiotensin. In 1934, Goldblatt et al. d …
Franz Volhard and Theodor Fahr: achievements and controversies in their research in renal disease and hypertension.
Heidland A, Gerabek W, Sebekova K. Heidland A, et al. J Hum Hypertens. 2001 Jan;15(1):5-16. doi: 10.1038/sj.jhh.1001130. J Hum Hypertens. 2001. PMID: 11223997 Review.
A very far reaching concept of Franz Volhard was his idea that pale (renal) hypertension results from a pressor substance released from ischaemic kidney(s) contributing--via a vicious circle--to a further rise in blood pressure with subsequent renovascular in …
A very far reaching concept of Franz Volhard was his idea that pale (renal) hypertension results from a pressor substance released fr …
Development of ideas on renovascular hypertension.
Peart S. Peart S. Semin Nephrol. 2000 Sep;20(5):388-93. Semin Nephrol. 2000. PMID: 11022890
The relation between high blood pressure and renal disease was established by Mahomed (1872). The discovery of renin and its possible link with Bright's disease was made by Tigerstedt and Bergman (1898), but only the experimental production of renal hypertension by …
The relation between high blood pressure and renal disease was established by Mahomed (1872). The discovery of renin and its possible …
11 results