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262 results
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Off the beaten pathway: the complex cross talk between Notch and NF-kappaB.
Osipo C, Golde TE, Osborne BA, Miele LA. Osipo C, et al. Among authors: golde te. Lab Invest. 2008 Jan;88(1):11-7. doi: 10.1038/labinvest.3700700. Epub 2007 Dec 3. Lab Invest. 2008. PMID: 18059366
ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a gamma-secretase inhibitor.
Osipo C, Patel P, Rizzo P, Clementz AG, Hao L, Golde TE, Miele L. Osipo C, et al. Among authors: golde te. Oncogene. 2008 Aug 28;27(37):5019-32. doi: 10.1038/onc.2008.149. Epub 2008 May 12. Oncogene. 2008. PMID: 18469855
Targeting Notch to target cancer stem cells.
Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, Osborne B, Miele L. Pannuti A, et al. Clin Cancer Res. 2010 Jun 15;16(12):3141-52. doi: 10.1158/1078-0432.CCR-09-2823. Epub 2010 Jun 8. Clin Cancer Res. 2010. PMID: 20530696 Free PMC article. Review.
Notch signaling in cancer.
Miele L, Golde T, Osborne B. Miele L, et al. Curr Mol Med. 2006 Dec;6(8):905-18. doi: 10.2174/156652406779010830. Curr Mol Med. 2006. PMID: 17168741 Review.
Targeting Notch signaling cross-talk with estrogen receptor and ErbB-2 in breast cancer.
Rizzo P, Osipo C, Pannuti A, Golde T, Osborne B, Miele L. Rizzo P, et al. Adv Enzyme Regul. 2009;49(1):134-41. doi: 10.1016/j.advenzreg.2009.01.008. Epub 2009 Jan 20. Adv Enzyme Regul. 2009. PMID: 19344631 Review. No abstract available.
p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1.
Yun J, Espinoza I, Pannuti A, Romero D, Martinez L, Caskey M, Stanculescu A, Bocchetta M, Rizzo P, Band V, Band H, Kim HM, Park SK, Kang KW, Avantaggiati ML, Gomez CR, Golde T, Osborne B, Miele L. Yun J, et al. J Cell Physiol. 2015 Dec;230(12):3115-27. doi: 10.1002/jcp.25052. J Cell Physiol. 2015. PMID: 26033683 Free PMC article.
Rational targeting of Notch signaling in cancer.
Rizzo P, Osipo C, Foreman K, Golde T, Osborne B, Miele L. Rizzo P, et al. Oncogene. 2008 Sep 1;27(38):5124-31. doi: 10.1038/onc.2008.226. Oncogene. 2008. PMID: 18758481 Review.
Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells.
Curry CL, Reed LL, Golde TE, Miele L, Nickoloff BJ, Foreman KE. Curry CL, et al. Among authors: golde te. Oncogene. 2005 Sep 22;24(42):6333-44. doi: 10.1038/sj.onc.1208783. Oncogene. 2005. PMID: 15940249
Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation.
Grudzien P, Lo S, Albain KS, Robinson P, Rajan P, Strack PR, Golde TE, Miele L, Foreman KE. Grudzien P, et al. Among authors: golde te. Anticancer Res. 2010 Oct;30(10):3853-67. Anticancer Res. 2010. PMID: 21036696
Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases.
Joshi I, Minter LM, Telfer J, Demarest RM, Capobianco AJ, Aster JC, Sicinski P, Fauq A, Golde TE, Osborne BA. Joshi I, et al. Among authors: golde te. Blood. 2009 Feb 19;113(8):1689-98. doi: 10.1182/blood-2008-03-147967. Epub 2008 Nov 10. Blood. 2009. PMID: 19001083 Free PMC article.
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