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Persephin, a novel neurotrophic factor related to GDNF and neurturin.
Milbrandt J, de Sauvage FJ, Fahrner TJ, Baloh RH, Leitner ML, Tansey MG, Lampe PA, Heuckeroth RO, Kotzbauer PT, Simburger KS, Golden JP, Davies JA, Vejsada R, Kato AC, Hynes M, Sherman D, Nishimura M, Wang LC, Vandlen R, Moffat B, Klein RD, Poulsen K, Gray C, Garces A, Johnson EM Jr, et al. Milbrandt J, et al. Among authors: golden jp. Neuron. 1998 Feb;20(2):245-53. doi: 10.1016/s0896-6273(00)80453-5. Neuron. 1998. PMID: 9491986 Free article.
GFRalpha3 is an orphan member of the GDNF/neurturin/persephin receptor family.
Baloh RH, Gorodinsky A, Golden JP, Tansey MG, Keck CL, Popescu NC, Johnson EM Jr, Milbrandt J. Baloh RH, et al. Among authors: golden jp. Proc Natl Acad Sci U S A. 1998 May 12;95(10):5801-6. doi: 10.1073/pnas.95.10.5801. Proc Natl Acad Sci U S A. 1998. PMID: 9576965 Free PMC article.
Analysis of the retrograde transport of glial cell line-derived neurotrophic factor (GDNF), neurturin, and persephin suggests that in vivo signaling for the GDNF family is GFRalpha coreceptor-specific.
Leitner ML, Molliver DC, Osborne PA, Vejsada R, Golden JP, Lampe PA, Kato AC, Milbrandt J, Johnson EM Jr. Leitner ML, et al. Among authors: golden jp. J Neurosci. 1999 Nov 1;19(21):9322-31. doi: 10.1523/JNEUROSCI.19-21-09322.1999. J Neurosci. 1999. PMID: 10531437 Free PMC article.
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