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Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c.
Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS. Liang G, et al. J Biol Chem. 2002 Mar 15;277(11):9520-8. doi: 10.1074/jbc.M111421200. Epub 2002 Jan 8. J Biol Chem. 2002. PMID: 11782483
Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis.
Goldstein JL, Rawson RB, Brown MS. Goldstein JL, et al. Arch Biochem Biophys. 2002 Jan 15;397(2):139-48. doi: 10.1006/abbi.2001.2615. Arch Biochem Biophys. 2002. PMID: 11795864 Review.
The SREBP pathway in Drosophila: regulation by palmitate, not sterols.
Seegmiller AC, Dobrosotskaya I, Goldstein JL, Ho YK, Brown MS, Rawson RB. Seegmiller AC, et al. Dev Cell. 2002 Feb;2(2):229-38. doi: 10.1016/s1534-5807(01)00119-8. Dev Cell. 2002. PMID: 11832248
Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
Yang T, Espenshade PJ, Wright ME, Yabe D, Gong Y, Aebersold R, Goldstein JL, Brown MS. Yang T, et al. Cell. 2002 Aug 23;110(4):489-500. doi: 10.1016/s0092-8674(02)00872-3. Cell. 2002. PMID: 12202038
Structure of the LDL receptor extracellular domain at endosomal pH.
Rudenko G, Henry L, Henderson K, Ichtchenko K, Brown MS, Goldstein JL, Deisenhofer J. Rudenko G, et al. Science. 2002 Dec 20;298(5602):2353-8. doi: 10.1126/science.1078124. Epub 2002 Nov 29. Science. 2002. PMID: 12459547
Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis.
Yabe D, Komuro R, Liang G, Goldstein JL, Brown MS. Yabe D, et al. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3155-60. doi: 10.1073/pnas.0130116100. Epub 2003 Mar 6. Proc Natl Acad Sci U S A. 2003. PMID: 12624180 Free PMC article.
Characterization of mouse short-chain aldehyde reductase (SCALD), an enzyme regulated by sterol regulatory element-binding proteins.
Kasus-Jacobi A, Ou J, Bashmakov YK, Shelton JM, Richardson JA, Goldstein JL, Brown MS. Kasus-Jacobi A, et al. J Biol Chem. 2003 Aug 22;278(34):32380-9. doi: 10.1074/jbc.M304969200. Epub 2003 Jun 13. J Biol Chem. 2003. PMID: 12807874
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