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2007 69
2008 70
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2011 89
2012 72
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2,210 results

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Page 1
The trans-Golgi-localized protein BICAT3 regulates manganese allocation and matrix polysaccharide biosynthesis.
He J, Yang B, Hause G, Rössner N, Peiter-Volk T, Schattat MH, Voiniciuc C, Peiter E. He J, et al. Plant Physiol. 2022 Nov 28;190(4):2579-2600. doi: 10.1093/plphys/kiac387. Plant Physiol. 2022. PMID: 35993897 Free PMC article.
Manganese (Mn2+) is essential for a diversity of processes, including photosynthetic water splitting and the transfer of glycosyl moieties. Various Golgi-localized glycosyltransferases that mediate cell wall matrix polysaccharide biosynthesis are Mn2+ dependent, but …
Manganese (Mn2+) is essential for a diversity of processes, including photosynthetic water splitting and the transfer of glycosyl moieties. …
Biophysical characterization of intrinsically disordered human Golgi matrix protein GRASP65.
Reddy ST, Uversky VN, Costa-Filho AJ. Reddy ST, et al. Int J Biol Macromol. 2020 Nov 1;162:1982-1993. doi: 10.1016/j.ijbiomac.2020.08.126. Epub 2020 Aug 18. Int J Biol Macromol. 2020. PMID: 32822731
Golgi Reassembly and Stacking Proteins (GRASPs), including GRASP65/GRASP55, were firstly found as stacking factors of Golgi cisternae. ...Here, we explored the structural features of human cis-Golgi GRASP65 in aqueous solution and compared them with th
Golgi Reassembly and Stacking Proteins (GRASPs), including GRASP65/GRASP55, were firstly found as stacking factors of Golgi
GOLGA4, A Golgi matrix protein, is dispensable for spermatogenesis and male fertility in mice.
Guo S, Chunyu Lv, Ouyang S, Wang X, Liao A, Yuan S. Guo S, et al. Biochem Biophys Res Commun. 2020 Aug 27;529(3):642-646. doi: 10.1016/j.bbrc.2020.05.170. Epub 2020 Jul 18. Biochem Biophys Res Commun. 2020. PMID: 32736686
Several Golgi-associated proteins were involved in this process. However, the specific function of Golgi-associated proteins, especially Golgi matrix protein, during acrosome biogenesis remains elusive. In this study, we identified …
Several Golgi-associated proteins were involved in this process. However, the specific function of Golgi-associated …
Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55/65.
Xiang Y, Zhang X, Nix DB, Katoh T, Aoki K, Tiemeyer M, Wang Y. Xiang Y, et al. Nat Commun. 2013;4:1659. doi: 10.1038/ncomms2669. Nat Commun. 2013. PMID: 23552074 Free PMC article.
GRASP65 and GRASP55, two proteins localized to the Golgi stack and early secretory pathway, mediate processes including Golgi stacking, Golgi ribbon linking and unconventional secretion. Previously, we have shown that GRASP depletion in cells disrupts …
GRASP65 and GRASP55, two proteins localized to the Golgi stack and early secretory pathway, mediate processes including Gol
GRASP55 regulates intra-Golgi localization of glycosylation enzymes to control glycosphingolipid biosynthesis.
Pothukuchi P, Agliarulo I, Pirozzi M, Rizzo R, Russo D, Turacchio G, Nüchel J, Yang JS, Gehin C, Capolupo L, Hernandez-Corbacho MJ, Biswas A, Vanacore G, Dathan N, Nitta T, Henklein P, Thattai M, Inokuchi JI, Hsu VW, Plomann M, Obeid LM, Hannun YA, Luini A, D'Angelo G, Parashuraman S. Pothukuchi P, et al. EMBO J. 2021 Oct 18;40(20):e107766. doi: 10.15252/embj.2021107766. Epub 2021 Sep 13. EMBO J. 2021. PMID: 34516001 Free PMC article.
How such compartmentalized localization of enzymes is achieved and how it contributes to glycosylation are not clear. Here, we show that the Golgi matrix protein GRASP55 directs the compartmentalized localization of key enzymes involved in glycosphingolipid ( …
How such compartmentalized localization of enzymes is achieved and how it contributes to glycosylation are not clear. Here, we show that the …
Protein lipidation.
Nadolski MJ, Linder ME. Nadolski MJ, et al. FEBS J. 2007 Oct;274(20):5202-10. doi: 10.1111/j.1742-4658.2007.06056.x. Epub 2007 Sep 24. FEBS J. 2007. PMID: 17892486 Free article. Review.
Palmitoylation facilitates the association of proteins with membranes, mediates protein trafficking, and more recently has been appreciated as a regulator of protein stability. ...Here we focus on DHHC proteins that modify Ras proteins in yeast …
Palmitoylation facilitates the association of proteins with membranes, mediates protein trafficking, and more recently has bee …
Exploring structural aspects of the human Golgi matrix protein GRASP55 in solution.
Reddy ST, Mendes LFS, Fontana NA, Costa-Filho AJ. Reddy ST, et al. Int J Biol Macromol. 2019 Aug 15;135:481-489. doi: 10.1016/j.ijbiomac.2019.05.089. Epub 2019 May 15. Int J Biol Macromol. 2019. PMID: 31102680
In mammals, the Golgi apparatus is the central hub for intracellular trafficking, sorting and post-translational modifications of proteins and lipids. Golgi reassembly and stacking proteins (GRASPs) are somehow involved in Golgi stacking, which …
In mammals, the Golgi apparatus is the central hub for intracellular trafficking, sorting and post-translational modifications of …
A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression.
Ghannoum S, Fantini D, Zahoor M, Reiterer V, Phuyal S, Leoncio Netto W, Sørensen Ø, Iyer A, Sengupta D, Prasmickaite L, Mælandsmo GM, Köhn-Luque A, Farhan H. Ghannoum S, et al. PLoS Comput Biol. 2023 Apr 17;19(4):e1010995. doi: 10.1371/journal.pcbi.1010995. eCollection 2023 Apr. PLoS Comput Biol. 2023. PMID: 37068117 Free PMC article.
As a biologically relevant example, we focused on Golgi fragmentation, a phenomenon often linked to alterations of cell migration. Golgi fragmentation was induced by depletion of Giantin, a Golgi matrix protein, the downregulation of which corre …
As a biologically relevant example, we focused on Golgi fragmentation, a phenomenon often linked to alterations of cell migration. …
Exploring liquid-liquid phase separation in the organisation of Golgi matrix proteins.
Mendes LFS, Oliveira CG, Simões KF, Kava E, Costa-Filho AJ. Mendes LFS, et al. Biochim Biophys Acta Proteins Proteom. 2024 Sep 1;1872(5):141029. doi: 10.1016/j.bbapap.2024.141029. Epub 2024 Jun 23. Biochim Biophys Acta Proteins Proteom. 2024. PMID: 38917877
The Golgi apparatus is a critical organelle in protein sorting and lipid metabolism. Characterized by its stacked, flattened cisternal structure, the Golgi exhibits distinct polarity with its cis- and trans-faces orchestrating various protein maturatio …
The Golgi apparatus is a critical organelle in protein sorting and lipid metabolism. Characterized by its stacked, flattened c …
Analysis of Golgi Protein Acetylation Using In Vitro Assays and Parallel Reaction Monitoring Mass Spectrometry.
Slade D, Hartl M. Slade D, et al. Methods Mol Biol. 2023;2557:721-741. doi: 10.1007/978-1-0716-2639-9_43. Methods Mol Biol. 2023. PMID: 36512247
Acetylation is one of the most abundant post-translational protein modifications that regulates all cellular compartments ranging from chromatin to cytoskeleton and Golgi. The dynamic acetylation of the Golgi stacking protein GRASP55 was shown to regul …
Acetylation is one of the most abundant post-translational protein modifications that regulates all cellular compartments ranging fro …
2,210 results