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Focal adhesion kinase and cancer.
Golubovskaya VM, Kweh FA, Cance WG. Golubovskaya VM, et al. Histol Histopathol. 2009 Apr;24(4):503-10. doi: 10.14670/HH-24.503. Histol Histopathol. 2009. PMID: 19224453 Review.
Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth.
Golubovskaya VM, Ho B, Zheng M, Magis A, Ostrov D, Morrison C, Cance WG. Golubovskaya VM, et al. BMC Cancer. 2013 Jul 11;13:342. doi: 10.1186/1471-2407-13-342. BMC Cancer. 2013. PMID: 23841915 Free PMC article.
FAK overexpression and p53 mutations are highly correlated in human breast cancer.
Golubovskaya VM, Conway-Dorsey K, Edmiston SN, Tse CK, Lark AA, Livasy CA, Moore D, Millikan RC, Cance WG. Golubovskaya VM, et al. Int J Cancer. 2009 Oct 1;125(7):1735-8. doi: 10.1002/ijc.24486. Int J Cancer. 2009. PMID: 19521985 Free PMC article.
The 7-amino-acid site in the proline-rich region of the N-terminal domain of p53 is involved in the interaction with FAK and is critical for p53 functioning.
Golubovskaya VM, Finch R, Zheng M, Kurenova EV, Cance WG. Golubovskaya VM, et al. Biochem J. 2008 Apr 1;411(1):151-60. doi: 10.1042/BJ20071657. Biochem J. 2008. PMID: 18215142
TAE226 inhibits human neuroblastoma cell survival.
Beierle EA, Trujillo A, Nagaram A, Golubovskaya VM, Cance WG, Kurenova EV. Beierle EA, et al. Cancer Invest. 2008 Mar;26(2):145-51. doi: 10.1080/07357900701577475. Cancer Invest. 2008. PMID: 18259944
Survival signaling through focal adhesion kinase in tumors.
Golubovskaya VM. Golubovskaya VM. Anticancer Agents Med Chem. 2013 May;13(4):531. doi: 10.2174/1871520611313040001. Anticancer Agents Med Chem. 2013. PMID: 22934710 No abstract available.
Editorial: Focal adhesion kinase signaling in cancer--Part II.
Golubovskaya VM. Golubovskaya VM. Anticancer Agents Med Chem. 2011 Sep;11(7):591-2. doi: 10.2174/187152011796817709. Anticancer Agents Med Chem. 2011. PMID: 21787274 No abstract available.
Focal adhesion kinase protein regulates Wnt3a gene expression to control cell fate specification in the developing neural plate.
Fonar Y, Gutkovich YE, Root H, Malyarova A, Aamar E, Golubovskaya VM, Elias S, Elkouby YM, Frank D. Fonar Y, et al. Mol Biol Cell. 2011 Jul 1;22(13):2409-21. doi: 10.1091/mbc.E10-12-0932. Epub 2011 May 5. Mol Biol Cell. 2011. PMID: 21551070 Free PMC article.
Targeting focal adhesion kinase in cancer-part I.
Golubovskaya VM. Golubovskaya VM. Anticancer Agents Med Chem. 2010 Dec;10(10):713. doi: 10.2174/187152010794728693. Anticancer Agents Med Chem. 2010. PMID: 21348852 No abstract available.
High focal adhesion kinase expression in breast carcinoma is associated with lymphovascular invasion and triple-negative phenotype.
Golubovskaya VM, Ylagan L, Miller A, Hughes M, Wilson J, Wang D, Brese E, Bshara W, Edge S, Morrison C, Cance WG. Golubovskaya VM, et al. BMC Cancer. 2014 Oct 17;14:769. doi: 10.1186/1471-2407-14-769. BMC Cancer. 2014. PMID: 25326692 Free PMC article.
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