Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
Cell. 2017 Jul 13;170(2):260-272.e8. doi: 10.1016/j.cell.2017.06.030.
Cell. 2017.
PMID: 28708996
Free PMC article.
To assist drug development through the identification of essential genes and pathways, we have measured competitive growth rates in mice of 2,578 barcoded Plasmodium berghei knockout mutants, representing >50% of the genome, and created a phenotype database. ...The leve …
To assist drug development through the identification of essential genes and pathways, we have measured competitive growth rates in mice of …