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Page 1
Challenges for the oral delivery of macromolecules.
Goldberg M, Gomez-Orellana I. Goldberg M, et al. Among authors: gomez orellana i. Nat Rev Drug Discov. 2003 Apr;2(4):289-95. doi: 10.1038/nrd1067. Nat Rev Drug Discov. 2003. PMID: 12669028 Review.
Oral delivery of insulin with the eligen technology: mechanistic studies.
Malkov D, Angelo R, Wang HZ, Flanders E, Tang H, Gomez-Orellana I. Malkov D, et al. Among authors: gomez orellana i. Curr Drug Deliv. 2005 Apr;2(2):191-7. doi: 10.2174/1567201053586001. Curr Drug Deliv. 2005. PMID: 16305420
Oral heparin: status review.
Arbit E, Goldberg M, Gomez-Orellana I, Majuru S. Arbit E, et al. Among authors: gomez orellana i. Thromb J. 2006 May 10;4:6. doi: 10.1186/1477-9560-4-6. Thromb J. 2006. PMID: 16686945 Free PMC article.
Strategies to improve oral drug bioavailability.
Gomez-Orellana I. Gomez-Orellana I. Expert Opin Drug Deliv. 2005 May;2(3):419-33. doi: 10.1517/17425247.2.3.419. Expert Opin Drug Deliv. 2005. PMID: 16296764 Review.
Oral absorption enhancement of cromolyn sodium through noncovalent complexation.
Ding X, Rath P, Angelo R, Stringfellow T, Flanders E, Dinh S, Gomez-Orellana I, Robinson JR. Ding X, et al. Among authors: gomez orellana i. Pharm Res. 2004 Dec;21(12):2196-206. doi: 10.1007/s11095-004-7671-9. Pharm Res. 2004. PMID: 15648250
Thermodynamic characterization of an intermediate state of human growth hormone.
Gomez-Orellana I, Variano B, Miura-Fraboni J, Milstein S, Paton DR. Gomez-Orellana I, et al. Protein Sci. 1998 Jun;7(6):1352-8. doi: 10.1002/pro.5560070611. Protein Sci. 1998. PMID: 9655339 Free PMC article.
Pharmacokinetics and pharmacodynamic effects of oral GLP-1 and PYY3-36: a proof-of-concept study in healthy subjects.
Beglinger C, Poller B, Arbit E, Ganzoni C, Gass S, Gomez-Orellana I, Drewe J. Beglinger C, et al. Among authors: gomez orellana i. Clin Pharmacol Ther. 2008 Oct;84(4):468-74. doi: 10.1038/clpt.2008.35. Clin Pharmacol Ther. 2008. PMID: 19238651
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