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Page 1
A cancer-associated point mutation disables the steric gate of human PrimPol.
Díaz-Talavera A, Calvo PA, González-Acosta D, Díaz M, Sastre-Moreno G, Blanco-Franco L, Guerra S, Martínez-Jiménez MI, Méndez J, Blanco L. Díaz-Talavera A, et al. Among authors: gonzalez acosta d. Sci Rep. 2019 Feb 4;9(1):1121. doi: 10.1038/s41598-018-37439-0. Sci Rep. 2019. PMID: 30718533 Free PMC article.
Functional interplay between c-Myc and Max in B lymphocyte differentiation.
Pérez-Olivares M, Trento A, Rodriguez-Acebes S, González-Acosta D, Fernández-Antorán D, Román-García S, Martinez D, López-Briones T, Torroja C, Carrasco YR, Méndez J, Moreno de Alborán I. Pérez-Olivares M, et al. Among authors: gonzalez acosta d. EMBO Rep. 2018 Oct;19(10):e45770. doi: 10.15252/embr.201845770. Epub 2018 Aug 20. EMBO Rep. 2018. PMID: 30126925 Free PMC article.
PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells.
Quinet A, Tirman S, Jackson J, Šviković S, Lemaçon D, Carvajal-Maldonado D, González-Acosta D, Vessoni AT, Cybulla E, Wood M, Tavis S, Batista LFZ, Méndez J, Sale JE, Vindigni A. Quinet A, et al. Among authors: gonzalez acosta d. Mol Cell. 2020 Feb 6;77(3):461-474.e9. doi: 10.1016/j.molcel.2019.10.008. Epub 2019 Oct 29. Mol Cell. 2020. PMID: 31676232 Free PMC article.
Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming.
Jacobs K, Doerdelmann C, Krietsch J, González-Acosta D, Mathis N, Kushinsky S, Guarino E, Gómez-Escolar C, Martinez D, Schmid JA, Leary PJ, Freire R, Ramiro AR, Eischen CM, Mendez J, Lopes M. Jacobs K, et al. Among authors: gonzalez acosta d. Mol Cell. 2022 Nov 3;82(21):4176-4188.e8. doi: 10.1016/j.molcel.2022.09.009. Epub 2022 Sep 23. Mol Cell. 2022. PMID: 36152632 Free PMC article.
Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity.
Palumbieri MD, Merigliano C, González-Acosta D, Kuster D, Krietsch J, Stoy H, von Känel T, Ulferts S, Welter B, Frey J, Doerdelmann C, Sanchi A, Grosse R, Chiolo I, Lopes M. Palumbieri MD, et al. Among authors: gonzalez acosta d. Nat Commun. 2023 Nov 28;14(1):7819. doi: 10.1038/s41467-023-43183-5. Nat Commun. 2023. PMID: 38016948 Free PMC article.
RAD51 restricts DNA over-replication from re-activated origins.
Muñoz S, Blanco-Romero E, González-Acosta D, Rodriguez-Acebes S, Megías D, Lopes M, Méndez J. Muñoz S, et al. Among authors: gonzalez acosta d. EMBO J. 2024 Mar;43(6):1043-1064. doi: 10.1038/s44318-024-00038-z. Epub 2024 Feb 15. EMBO J. 2024. PMID: 38360996 Free PMC article.