Gonzalez FJ - Search Results

1

Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1.

Gonzalez FJ. Gonzalez FJ. Mutat Res. 2005 Jan 6;569(1-2):101-10. doi: 10.1016/j.mrfmmm.2004.04.021. Mutat Res. 2005. PMID: 15603755 Review.

2

6β-hydroxytestosterone, a cytochrome P450 1B1 metabolite of testosterone, contributes to angiotensin II-induced hypertension and its pathogenesis in male mice.

Pingili AK, Kara M, Khan NS, Estes AM, Lin Z, Li W, Gonzalez FJ, Malik KU. Pingili AK, et al. Among authors: gonzalez fj. Hypertension. 2015 Jun;65(6):1279-87. doi: 10.1161/HYPERTENSIONAHA.115.05396. Epub 2015 Apr 13. Hypertension. 2015. PMID: 25870196 Free PMC article.

3

Estrogen metabolism by cytochrome P450 1B1 modulates the hypertensive effect of angiotensin II in female mice.

Jennings BL, George LW, Pingili AK, Khan NS, Estes AM, Fang XR, Gonzalez FJ, Malik KU. Jennings BL, et al. Among authors: gonzalez fj. Hypertension. 2014 Jul;64(1):134-40. doi: 10.1161/HYPERTENSIONAHA.114.03275. Epub 2014 Apr 28. Hypertension. 2014. PMID: 24777982 Free PMC article.

4

Hepatic sirtuin 1 is dispensable for fibrate-induced peroxisome proliferator-activated receptor-α function in vivo.

Bonzo JA, Brocker C, Jiang C, Wang RH, Deng CX, Gonzalez FJ. Bonzo JA, et al. Among authors: gonzalez fj. Am J Physiol Endocrinol Metab. 2014 Apr 1;306(7):E824-37. doi: 10.1152/ajpendo.00175.2013. Epub 2014 Feb 4. Am J Physiol Endocrinol Metab. 2014. PMID: 24496310 Free PMC article.

5

Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha.

Cheung C, Akiyama TE, Ward JM, Nicol CJ, Feigenbaum L, Vinson C, Gonzalez FJ. Cheung C, et al. Among authors: gonzalez fj. Cancer Res. 2004 Jun 1;64(11):3849-54. doi: 10.1158/0008-5472.CAN-04-0322. Cancer Res. 2004. PMID: 15172993

6

Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans.

Takahashi S, Fukami T, Masuo Y, Brocker CN, Xie C, Krausz KW, Wolf CR, Henderson CJ, Gonzalez FJ. Takahashi S, et al. Among authors: gonzalez fj. J Lipid Res. 2016 Dec;57(12):2130-2137. doi: 10.1194/jlr.M071183. Epub 2016 Sep 16. J Lipid Res. 2016. PMID: 27638959 Free PMC article.

7

Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4alpha.

Inoue Y, Yu AM, Yim SH, Ma X, Krausz KW, Inoue J, Xiang CC, Brownstein MJ, Eggertsen G, Björkhem I, Gonzalez FJ. Inoue Y, et al. Among authors: gonzalez fj. J Lipid Res. 2006 Jan;47(1):215-27. doi: 10.1194/jlr.M500430-JLR200. Epub 2005 Nov 1. J Lipid Res. 2006. PMID: 16264197 Free PMC article.

8

Identification of noninvasive biomarkers for alcohol-induced liver disease using urinary metabolomics and the Ppara-null mouse.

Manna SK, Patterson AD, Yang Q, Krausz KW, Li H, Idle JR, Fornace AJ Jr, Gonzalez FJ. Manna SK, et al. Among authors: gonzalez fj. J Proteome Res. 2010 Aug 6;9(8):4176-88. doi: 10.1021/pr100452b. J Proteome Res. 2010. PMID: 20540569 Free PMC article.

9

Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge.

Cho JY, Matsubara T, Kang DW, Ahn SH, Krausz KW, Idle JR, Luecke H, Gonzalez FJ. Cho JY, et al. Among authors: gonzalez fj. J Lipid Res. 2010 May;51(5):1063-74. doi: 10.1194/jlr.M002923. Epub 2009 Nov 9. J Lipid Res. 2010. PMID: 19965603 Free PMC article.

10

Serum metabolomics reveals irreversible inhibition of fatty acid beta-oxidation through the suppression of PPARalpha activation as a contributing mechanism of acetaminophen-induced hepatotoxicity.

Chen C, Krausz KW, Shah YM, Idle JR, Gonzalez FJ. Chen C, et al. Among authors: gonzalez fj. Chem Res Toxicol. 2009 Apr;22(4):699-707. doi: 10.1021/tx800464q. Chem Res Toxicol. 2009. PMID: 19256530 Free PMC article.

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