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Metabolomics.
Idle JR, Gonzalez FJ. Idle JR, et al. Among authors: gonzalez fj. Cell Metab. 2007 Nov;6(5):348-51. doi: 10.1016/j.cmet.2007.10.005. Cell Metab. 2007. PMID: 17983580 Free PMC article.
Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and Cyp2e1-null mice.
Chen C, Krausz KW, Idle JR, Gonzalez FJ. Chen C, et al. Among authors: gonzalez fj. J Biol Chem. 2008 Feb 22;283(8):4543-59. doi: 10.1074/jbc.M706299200. Epub 2007 Dec 19. J Biol Chem. 2008. PMID: 18093979 Free PMC article.
Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation.
Cho JY, Kang DW, Ma X, Ahn SH, Krausz KW, Luecke H, Idle JR, Gonzalez FJ. Cho JY, et al. Among authors: gonzalez fj. J Lipid Res. 2009 May;50(5):924-37. doi: 10.1194/jlr.M800647-JLR200. Epub 2009 Jan 13. J Lipid Res. 2009. PMID: 19141872 Free PMC article.
Fenofibrate metabolism in the cynomolgus monkey using ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry-based metabolomics.
Liu A, Patterson AD, Yang Z, Zhang X, Liu W, Qiu F, Sun H, Krausz KW, Idle JR, Gonzalez FJ, Dai R. Liu A, et al. Among authors: gonzalez fj. Drug Metab Dispos. 2009 Jun;37(6):1157-63. doi: 10.1124/dmd.108.025817. Epub 2009 Feb 27. Drug Metab Dispos. 2009. PMID: 19251819 Free PMC article.
Radiation metabolomics. 3. Biomarker discovery in the urine of gamma-irradiated rats using a simplified metabolomics protocol of gas chromatography-mass spectrometry combined with random forests machine learning algorithm.
Lanz C, Patterson AD, Slavík J, Krausz KW, Ledermann M, Gonzalez FJ, Idle JR. Lanz C, et al. Among authors: gonzalez fj. Radiat Res. 2009 Aug;172(2):198-212. doi: 10.1667/RR1796.1. Radiat Res. 2009. PMID: 19630524 Free PMC article.
The role of mass spectrometry-based metabolomics in medical countermeasures against radiation.
Patterson AD, Lanz C, Gonzalez FJ, Idle JR. Patterson AD, et al. Among authors: gonzalez fj. Mass Spectrom Rev. 2010 May-Jun;29(3):503-21. doi: 10.1002/mas.20272. Mass Spectrom Rev. 2010. PMID: 19890938 Free PMC article. Review.
A comprehensive understanding of thioTEPA metabolism in the mouse using UPLC-ESI-QTOFMS-based metabolomics.
Li F, Patterson AD, Höfer CC, Krausz KW, Gonzalez FJ, Idle JR. Li F, et al. Among authors: gonzalez fj. Biochem Pharmacol. 2011 Apr 15;81(8):1043-53. doi: 10.1016/j.bcp.2011.01.024. Epub 2011 Feb 12. Biochem Pharmacol. 2011. PMID: 21300029 Free PMC article.
UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model.
Manna SK, Patterson AD, Yang Q, Krausz KW, Idle JR, Fornace AJ, Gonzalez FJ. Manna SK, et al. Among authors: gonzalez fj. J Proteome Res. 2011 Sep 2;10(9):4120-33. doi: 10.1021/pr200310s. Epub 2011 Jul 28. J Proteome Res. 2011. PMID: 21749142 Free PMC article.
Xenobiotic metabolomics: major impact on the metabolome.
Johnson CH, Patterson AD, Idle JR, Gonzalez FJ. Johnson CH, et al. Among authors: gonzalez fj. Annu Rev Pharmacol Toxicol. 2012;52:37-56. doi: 10.1146/annurev-pharmtox-010611-134748. Epub 2011 Aug 3. Annu Rev Pharmacol Toxicol. 2012. PMID: 21819238 Free PMC article. Review.
Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling.
Patterson AD, Maurhofer O, Beyoglu D, Lanz C, Krausz KW, Pabst T, Gonzalez FJ, Dufour JF, Idle JR. Patterson AD, et al. Among authors: gonzalez fj. Cancer Res. 2011 Nov 1;71(21):6590-600. doi: 10.1158/0008-5472.CAN-11-0885. Epub 2011 Sep 7. Cancer Res. 2011. PMID: 21900402 Free PMC article.
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