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A transgenic mouse expressing human CYP1A2 in the pancreas.
Ueno T, Tamura S, Frels WI, Shou M, Gonzalez FJ, Kimura S. Ueno T, et al. Among authors: gonzalez fj. Biochem Pharmacol. 2000 Sep 15;60(6):857-63. doi: 10.1016/s0006-2952(00)00389-0. Biochem Pharmacol. 2000. PMID: 10930541
Comparison of substrate metabolism by wild type CYP2D6 protein and a variant containing methionine, not valine, at position 374.
Crespi CL, Steimel DT, Penman BW, Korzekwa KR, Fernandez-Salguero P, Buters JT, Gelboin HV, Gonzalez FJ, Idle JR, Daly AK. Crespi CL, et al. Among authors: gonzalez fj. Pharmacogenetics. 1995 Aug;5(4):234-43. doi: 10.1097/00008571-199508000-00007. Pharmacogenetics. 1995. PMID: 8528270
We have analysed kinetic parameters of cDNA-derived CYP2D6 proteins derived from the original CYP2D6 cDNA isolate (Gonzalez FJ et al. Nature 1988: 331, 442-446) which contains methionine at position 374 (CYP2D6-Met) and a modified cDNA which contains valine at posit …
We have analysed kinetic parameters of cDNA-derived CYP2D6 proteins derived from the original CYP2D6 cDNA isolate (Gonzalez FJ
1,432 results