Gonzalez FJ - Search Results

1

Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives: enzyme specificity, interindividual distribution and metabolic contribution in human liver.

Shou M, Martinet M, Korzekwa KR, Krausz KW, Gonzalez FJ, Gelboin HV. Shou M, et al. Among authors: gonzalez fj. Pharmacogenetics. 1998 Oct;8(5):391-401. doi: 10.1097/00008571-199810000-00004. Pharmacogenetics. 1998. PMID: 9825831

2

The rat P450 IID subfamily: complete sequences of four closely linked genes and evidence that gene conversions maintained sequence homogeneity at the heme-binding region of the cytochrome P450 active site.

Matsunaga E, Umeno M, Gonzalez FJ. Matsunaga E, et al. Among authors: gonzalez fj. J Mol Evol. 1990 Feb;30(2):155-69. doi: 10.1007/BF02099942. J Mol Evol. 1990. PMID: 2107330

3

A transgenic mouse expressing human CYP1A2 in the pancreas.

Ueno T, Tamura S, Frels WI, Shou M, Gonzalez FJ, Kimura S. Ueno T, et al. Among authors: gonzalez fj. Biochem Pharmacol. 2000 Sep 15;60(6):857-63. doi: 10.1016/s0006-2952(00)00389-0. Biochem Pharmacol. 2000. PMID: 10930541

4

Comparison of human mouse P1450 upstream regulatory sequences in liver- and nonliver-derived cell lines.

Jaiswal AK, Gonzalez FJ, Nebert DW. Jaiswal AK, et al. Among authors: gonzalez fj. Mol Endocrinol. 1987 Apr;1(4):312-20. doi: 10.1210/mend-1-4-312. Mol Endocrinol. 1987. PMID: 3453896

5

Human cytochrome P4502B6: interindividual hepatic expression, substrate specificity, and role in procarcinogen activation.

Code EL, Crespi CL, Penman BW, Gonzalez FJ, Chang TK, Waxman DJ. Code EL, et al. Among authors: gonzalez fj. Drug Metab Dispos. 1997 Aug;25(8):985-93. Drug Metab Dispos. 1997. PMID: 9280407

6

Coexpression of cytochrome P4502A6 and human NADPH-P450 oxidoreductase in the baculovirus system.

Chen L, Buters JT, Hardwick JP, Tamura S, Penman BW, Gonzalez FJ, Crespi CL. Chen L, et al. Among authors: gonzalez fj. Drug Metab Dispos. 1997 Apr;25(4):399-405. Drug Metab Dispos. 1997. PMID: 9107537

7

Comparison of substrate metabolism by wild type CYP2D6 protein and a variant containing methionine, not valine, at position 374.

Crespi CL, Steimel DT, Penman BW, Korzekwa KR, Fernandez-Salguero P, Buters JT, Gelboin HV, Gonzalez FJ, Idle JR, Daly AK. Crespi CL, et al. Among authors: gonzalez fj. Pharmacogenetics. 1995 Aug;5(4):234-43. doi: 10.1097/00008571-199508000-00007. Pharmacogenetics. 1995. PMID: 8528270

We have analysed kinetic parameters of cDNA-derived CYP2D6 proteins derived from the original CYP2D6 cDNA isolate (Gonzalez FJ et al. Nature 1988: 331, 442-446) which contains methionine at position 374 (CYP2D6-Met) and a modified cDNA which contains valine at posit …

We have analysed kinetic parameters of cDNA-derived CYP2D6 proteins derived from the original CYP2D6 cDNA isolate (Gonzalez FJ …

8

Characterization of a human cell line expressing high levels of cDNA-derived CYP2D6.

Penman BW, Reece J, Smith T, Yang CS, Gelboin HV, Gonzalez FJ, Crespi CL. Penman BW, et al. Among authors: gonzalez fj. Pharmacogenetics. 1993 Feb;3(1):28-39. doi: 10.1097/00008571-199302000-00003. Pharmacogenetics. 1993. PMID: 8485585

9

Retroviral mediated expression of human cytochrome P450 2A6 in C3H/10T1/2 cells confers transformability by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

Tiano HF, Hosokawa M, Chulada PC, Smith PB, Wang RL, Gonzalez FJ, Crespi CL, Langenbach R. Tiano HF, et al. Among authors: gonzalez fj. Carcinogenesis. 1993 Jul;14(7):1421-7. doi: 10.1093/carcin/14.7.1421. Carcinogenesis. 1993. PMID: 8330360

10

Role of CYP1A2 in caffeine pharmacokinetics and metabolism: studies using mice deficient in CYP1A2.

Buters JT, Tang BK, Pineau T, Gelboin HV, Kimura S, Gonzalez FJ. Buters JT, et al. Among authors: gonzalez fj. Pharmacogenetics. 1996 Aug;6(4):291-6. doi: 10.1097/00008571-199608000-00002. Pharmacogenetics. 1996. PMID: 8873215

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