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Thermally activated TRP channels: molecular sensors for temperature detection.
Castillo K, Diaz-Franulic I, Canan J, Gonzalez-Nilo F, Latorre R. Castillo K, et al. Phys Biol. 2018 Jan 24;15(2):021001. doi: 10.1088/1478-3975/aa9a6f. Phys Biol. 2018. PMID: 29135465 Review.
Dissection of the components for PIP2 activation and thermosensation in TRP channels.
Brauchi S, Orta G, Mascayano C, Salazar M, Raddatz N, Urbina H, Rosenmann E, Gonzalez-Nilo F, Latorre R. Brauchi S, et al. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10246-51. doi: 10.1073/pnas.0703420104. Epub 2007 Jun 4. Proc Natl Acad Sci U S A. 2007. PMID: 17548815 Free PMC article.
Study of the interaction between progesterone and beta-cyclodextrin by electrochemical techniques and steered molecular dynamics.
Caballero J, Zamora C, Aguayo D, Yañez C, González-Nilo FD. Caballero J, et al. J Phys Chem B. 2008 Aug 21;112(33):10194-201. doi: 10.1021/jp8006766. Epub 2008 Jul 30. J Phys Chem B. 2008. PMID: 18665626
The pH sensor of the plant K+-uptake channel KAT1 is built from a sensory cloud rather than from single key amino acids.
González W, Riedelsberger J, Morales-Navarro SE, Caballero J, Alzate-Morales JH, González-Nilo FD, Dreyer I. González W, et al. Biochem J. 2012 Feb 15;442(1):57-63. doi: 10.1042/BJ20111498. Biochem J. 2012. PMID: 22070190
Molecular determinants of phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) binding to transient receptor potential V1 (TRPV1) channels.
Poblete H, Oyarzún I, Olivero P, Comer J, Zuñiga M, Sepulveda RV, Báez-Nieto D, González Leon C, González-Nilo F, Latorre R. Poblete H, et al. J Biol Chem. 2015 Jan 23;290(4):2086-98. doi: 10.1074/jbc.M114.613620. Epub 2014 Nov 25. J Biol Chem. 2015. PMID: 25425643 Free PMC article.
Hydrophobic interaction between contiguous residues in the S6 transmembrane segment acts as a stimuli integration node in the BK channel.
Carrasquel-Ursulaez W, Contreras GF, Sepúlveda RV, Aguayo D, González-Nilo F, González C, Latorre R. Carrasquel-Ursulaez W, et al. J Gen Physiol. 2015 Jan;145(1):61-74. doi: 10.1085/jgp.201411194. J Gen Physiol. 2015. PMID: 25548136 Free PMC article.
Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels.
Garcia-Elias A, Berna-Erro A, Rubio-Moscardo F, Pardo-Pastor C, Mrkonjić S, Sepúlveda RV, Vicente R, González-Nilo F, Valverde MA. Garcia-Elias A, et al. Structure. 2015 Aug 4;23(8):1404-1413. doi: 10.1016/j.str.2015.05.018. Epub 2015 Jul 2. Structure. 2015. PMID: 26146187
Pore dimensions and the role of occupancy in unitary conductance of Shaker K channels.
Díaz-Franulic I, Sepúlveda RV, Navarro-Quezada N, González-Nilo F, Naranjo D. Díaz-Franulic I, et al. J Gen Physiol. 2015 Aug;146(2):133-46. doi: 10.1085/jgp.201411353. J Gen Physiol. 2015. PMID: 26216859 Free PMC article.
Effective pore size and radius of capture for K(+) ions in K-channels.
Moldenhauer H, Díaz-Franulic I, González-Nilo F, Naranjo D. Moldenhauer H, et al. Sci Rep. 2016 Feb 2;6:19893. doi: 10.1038/srep19893. Sci Rep. 2016. PMID: 26831782 Free PMC article.
β1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel.
Castillo JP, Sánchez-Rodríguez JE, Hyde HC, Zaelzer CA, Aguayo D, Sepúlveda RV, Luk LY, Kent SB, Gonzalez-Nilo FD, Bezanilla F, Latorre R. Castillo JP, et al. Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):E3231-9. doi: 10.1073/pnas.1606381113. Epub 2016 May 23. Proc Natl Acad Sci U S A. 2016. PMID: 27217576 Free PMC article.
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