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Covalent coercion by Legionella pneumophila.
Itzen A, Goody RS. Itzen A, et al. Cell Host Microbe. 2011 Aug 18;10(2):89-91. doi: 10.1016/j.chom.2011.08.002. Cell Host Microbe. 2011. PMID: 21843863
Modulation of small GTPases by Legionella.
Goody RS, Itzen A. Goody RS, et al. Curr Top Microbiol Immunol. 2013;376:117-33. doi: 10.1007/82_2013_340. Curr Top Microbiol Immunol. 2013. PMID: 23918171 Review.
The versatile Legionella effector protein DrrA.
Goody RS, Müller MP, Schoebel S, Oesterlin LK, Blümer J, Peters H, Blankenfeldt W, Itzen A. Goody RS, et al. Commun Integr Biol. 2011 Jan;4(1):72-4. doi: 10.4161/cib.4.1.13857. Commun Integr Biol. 2011. PMID: 21509184 Free PMC article.
Adenylylation: renaissance of a forgotten post-translational modification.
Itzen A, Blankenfeldt W, Goody RS. Itzen A, et al. Trends Biochem Sci. 2011 Apr;36(4):221-8. doi: 10.1016/j.tibs.2010.12.004. Epub 2011 Jan 20. Trends Biochem Sci. 2011. PMID: 21256032 Review.
Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase.
Deraeve C, Guo Z, Bon RS, Blankenfeldt W, DiLucrezia R, Wolf A, Menninger S, Stigter EA, Wetzel S, Choidas A, Alexandrov K, Waldmann H, Goody RS, Wu YW. Deraeve C, et al. J Am Chem Soc. 2012 May 2;134(17):7384-91. doi: 10.1021/ja211305j. Epub 2012 Apr 22. J Am Chem Soc. 2012. PMID: 22480322
Protein LidA from Legionella is a Rab GTPase supereffector.
Schoebel S, Cichy AL, Goody RS, Itzen A. Schoebel S, et al. Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):17945-50. doi: 10.1073/pnas.1113133108. Epub 2011 Oct 19. Proc Natl Acad Sci U S A. 2011. PMID: 22011575 Free PMC article.
Identification and specificity profiling of protein prenyltransferase inhibitors using new fluorescent phosphoisoprenoids.
Dursina B, Reents R, Delon C, Wu Y, Kulharia M, Thutewohl M, Veligodsky A, Kalinin A, Evstifeev V, Ciobanu D, Szedlacsek SE, Waldmann H, Goody RS, Alexandrov K. Dursina B, et al. J Am Chem Soc. 2006 Mar 8;128(9):2822-35. doi: 10.1021/ja052196e. J Am Chem Soc. 2006. PMID: 16506760
Characterization of enzymes from Legionella pneumophila involved in reversible adenylylation of Rab1 protein.
Müller MP, Shkumatov AV, Oesterlin LK, Schoebel S, Goody PR, Goody RS, Itzen A. Müller MP, et al. J Biol Chem. 2012 Oct 12;287(42):35036-46. doi: 10.1074/jbc.M112.396861. Epub 2012 Aug 7. J Biol Chem. 2012. PMID: 22872634 Free PMC article.
The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting.
Li F, Yi L, Zhao L, Itzen A, Goody RS, Wu YW. Li F, et al. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2572-7. doi: 10.1073/pnas.1313655111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24550285 Free PMC article.
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