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STIM1 elevation in the heart results in aberrant Ca²⁺ handling and cardiomyopathy.
Correll RN, Goonasekera SA, van Berlo JH, Burr AR, Accornero F, Zhang H, Makarewich CA, York AJ, Sargent MA, Chen X, Houser SR, Molkentin JD. Correll RN, et al. Among authors: goonasekera sa. J Mol Cell Cardiol. 2015 Oct;87:38-47. doi: 10.1016/j.yjmcc.2015.07.032. Epub 2015 Aug 1. J Mol Cell Cardiol. 2015. PMID: 26241845 Free PMC article.
Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice.
Elrod JW, Wong R, Mishra S, Vagnozzi RJ, Sakthievel B, Goonasekera SA, Karch J, Gabel S, Farber J, Force T, Brown JH, Murphy E, Molkentin JD. Elrod JW, et al. Among authors: goonasekera sa. J Clin Invest. 2010 Oct;120(10):3680-7. doi: 10.1172/JCI43171. Epub 2010 Sep 20. J Clin Invest. 2010. PMID: 20890047 Free PMC article.
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