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MVA-5T4-induced immune responses are an early marker of efficacy in renal cancer patients.
Harrop R, Shingler WH, McDonald M, Treasure P, Amato RJ, Hawkins RE, Kaufman HL, de Belin J, Kelleher M, Goonewardena M, Naylor S. Harrop R, et al. Among authors: goonewardena m. Cancer Immunol Immunother. 2011 Jun;60(6):829-37. doi: 10.1007/s00262-011-0993-7. Epub 2011 Mar 9. Cancer Immunol Immunother. 2011. PMID: 21387109 Clinical Trial.
Vaccination of renal cell cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) alone or administered in combination with interferon-alpha (IFN-alpha): a phase 2 trial.
Amato RJ, Shingler W, Goonewardena M, de Belin J, Naylor S, Jac J, Willis J, Saxena S, Hernandez-McClain J, Harrop R. Amato RJ, et al. Among authors: goonewardena m. J Immunother. 2009 Sep;32(7):765-72. doi: 10.1097/CJI.0b013e3181ace876. J Immunother. 2009. PMID: 19561532 Clinical Trial.
Vaccination of metastatic renal cancer patients with MVA-5T4: a randomized, double-blind, placebo-controlled phase III study.
Amato RJ, Hawkins RE, Kaufman HL, Thompson JA, Tomczak P, Szczylik C, McDonald M, Eastty S, Shingler WH, de Belin J, Goonewardena M, Naylor S, Harrop R. Amato RJ, et al. Among authors: goonewardena m. Clin Cancer Res. 2010 Nov 15;16(22):5539-47. doi: 10.1158/1078-0432.CCR-10-2082. Epub 2010 Sep 29. Clin Cancer Res. 2010. PMID: 20881001 Clinical Trial.