Gopalappa R - Search Results

1

Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia.

Lim JS, Gopalappa R, Kim SH, Ramakrishna S, Lee M, Kim WI, Kim J, Park SM, Lee J, Oh JH, Kim HD, Park CH, Lee JS, Kim S, Kim DS, Han JM, Kang HC, Kim HH, Lee JH. Lim JS, et al. Among authors: gopalappa r. Am J Hum Genet. 2017 Mar 2;100(3):454-472. doi: 10.1016/j.ajhg.2017.01.030. Epub 2017 Feb 16. Am J Hum Genet. 2017. PMID: 28215400 Free PMC article.

2

Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations.

Ramakrishna S, Cho SW, Kim S, Song M, Gopalappa R, Kim JS, Kim H. Ramakrishna S, et al. Among authors: gopalappa r. Nat Commun. 2014 Feb 26;5:3378. doi: 10.1038/ncomms4378. Nat Commun. 2014. PMID: 24569644 Free article.

3

Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA.

Ramakrishna S, Kwaku Dad AB, Beloor J, Gopalappa R, Lee SK, Kim H. Ramakrishna S, et al. Among authors: gopalappa r. Genome Res. 2014 Jun;24(6):1020-7. doi: 10.1101/gr.171264.113. Epub 2014 Apr 2. Genome Res. 2014. PMID: 24696462 Free PMC article.

4

Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption.

Gopalappa R, Suresh B, Ramakrishna S, Kim HH. Gopalappa R, et al. Nucleic Acids Res. 2018 Jul 6;46(12):e71. doi: 10.1093/nar/gky222. Nucleic Acids Res. 2018. PMID: 29584876 Free PMC article.

5

Efficient genome editing by FACS enrichment of paired D10A Cas9 nickases coupled with fluorescent proteins.

Gopalappa R, Song M, Chandrasekaran AP, Das S, Haq S, Koh HC, Ramakrishna S. Gopalappa R, et al. Arch Pharm Res. 2018 Sep;41(9):911-920. doi: 10.1007/s12272-018-1042-2. Epub 2018 May 31. Arch Pharm Res. 2018. PMID: 29855892

6

En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements.

Lee HJ, Gopalappa R, Sunwoo H, Choi SW, Ramakrishna S, Lee JT, Kim HH, Nam JW. Lee HJ, et al. Among authors: gopalappa r. Nucleic Acids Res. 2019 May 7;47(8):3875-3887. doi: 10.1093/nar/gkz109. Nucleic Acids Res. 2019. PMID: 30783652 Free PMC article.

7

Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases.

Jang H, Jo DH, Cho CS, Shin JH, Seo JH, Yu G, Gopalappa R, Kim D, Cho SR, Kim JH, Kim HH. Jang H, et al. Among authors: gopalappa r. Nat Biomed Eng. 2022 Feb;6(2):181-194. doi: 10.1038/s41551-021-00788-9. Epub 2021 Aug 26. Nat Biomed Eng. 2022. PMID: 34446856

8

In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model.

Noh B, Rim JH, Gopalappa R, Lin H, Kim KM, Kang MJ, Gee HY, Choi JY, Kim HH, Jung J. Noh B, et al. Among authors: gopalappa r. Theranostics. 2022 Feb 28;12(5):2465-2482. doi: 10.7150/thno.67781. eCollection 2022. Theranostics. 2022. PMID: 35265220 Free PMC article.

9

Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling.

Kwak M, Southard KM, Kim WR, Lin A, Kim NH, Gopalappa R, Lee HJ, An M, Choi SH, Jung Y, Noh K, Farlow J, Georgakopoulos A, Robakis NK, Kang MK, Kutys ML, Seo D, Kim HH, Kim YH, Cheon J, Gartner ZJ, Jun YW. Kwak M, et al. Among authors: gopalappa r. Nat Cell Biol. 2022 Dec;24(12):1739-1753. doi: 10.1038/s41556-022-01031-6. Epub 2022 Dec 1. Nat Cell Biol. 2022. PMID: 36456828 Free PMC article.

10

CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis.

Rim JH, Gopalappa R, Gee HY. Rim JH, et al. Among authors: gopalappa r. N Engl J Med. 2021 Oct 28;385(18):1722. doi: 10.1056/NEJMc2114592. N Engl J Med. 2021. PMID: 34706180 No abstract available.

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