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Induction of connective tissue growth factor (CTGF) in human endothelial cells by lysophosphatidic acid, sphingosine-1-phosphate, and platelets.
Muehlich S, Schneider N, Hinkmann F, Garlichs CD, Goppelt-Struebe M. Muehlich S, et al. Atherosclerosis. 2004 Aug;175(2):261-8. doi: 10.1016/j.atherosclerosis.2004.04.011. Atherosclerosis. 2004. PMID: 15262182
Inhibition of Rho kinases increases directional motility of microvascular endothelial cells.
Breyer J, Samarin J, Rehm M, Lautscham L, Fabry B, Goppelt-Struebe M. Breyer J, et al. Biochem Pharmacol. 2012 Mar 1;83(5):616-26. doi: 10.1016/j.bcp.2011.12.012. Epub 2011 Dec 16. Biochem Pharmacol. 2012. PMID: 22192821
Inhibitors of oxygen sensing prolyl hydroxylases regulate nuclear localization of the transcription factors Smad2 and YAP/TAZ involved in CTGF synthesis.
Preisser F, Giehl K, Rehm M, Goppelt-Struebe M. Preisser F, et al. Biochim Biophys Acta. 2016 Aug;1863(8):2027-36. doi: 10.1016/j.bbamcr.2016.05.001. Epub 2016 May 5. Biochim Biophys Acta. 2016. PMID: 27155083
Actin-mediated gene expression depends on RhoA and Rac1 signaling in proximal tubular epithelial cells.
Giehl K, Keller C, Muehlich S, Goppelt-Struebe M. Giehl K, et al. PLoS One. 2015 Mar 27;10(3):e0121589. doi: 10.1371/journal.pone.0121589. eCollection 2015. PLoS One. 2015. PMID: 25816094 Free PMC article.
HIF-1α activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cells.
Weidemann A, Breyer J, Rehm M, Eckardt KU, Daniel C, Cicha I, Giehl K, Goppelt-Struebe M. Weidemann A, et al. Cell Commun Signal. 2013 Oct 21;11:80. doi: 10.1186/1478-811X-11-80. Cell Commun Signal. 2013. PMID: 24144209 Free PMC article.
FoxO proteins mediate hypoxic induction of connective tissue growth factor in endothelial cells.
Samarin J, Wessel J, Cicha I, Kroening S, Warnecke C, Goppelt-Struebe M. Samarin J, et al. J Biol Chem. 2010 Feb 12;285(7):4328-36. doi: 10.1074/jbc.M109.049650. Epub 2009 Dec 16. J Biol Chem. 2010. PMID: 20018872 Free PMC article.
Vectorial secretion of CTGF as a cell-type specific response to LPA and TGF-β in human tubular epithelial cells.
Zuehlke J, Ebenau A, Krueger B, Goppelt-Struebe M. Zuehlke J, et al. Cell Commun Signal. 2012 Sep 2;10(1):25. doi: 10.1186/1478-811X-10-25. Cell Commun Signal. 2012. PMID: 22938209 Free PMC article.
Receptor-independent modulation of TGF-β-induced pro-fibrotic pathways by relaxin-2 in human primary tubular epithelial cells.
Grampp S, Goppelt-Struebe M. Grampp S, et al. Among authors: goppelt struebe m. Cell Tissue Res. 2018 Dec;374(3):619-627. doi: 10.1007/s00441-018-2904-0. Epub 2018 Aug 4. Cell Tissue Res. 2018. PMID: 30078103
Characterization of connective tissue growth factor expression in primary cultures of human tubular epithelial cells: modulation by hypoxia.
Kroening S, Neubauer E, Wullich B, Aten J, Goppelt-Struebe M. Kroening S, et al. Am J Physiol Renal Physiol. 2010 Mar;298(3):F796-806. doi: 10.1152/ajprenal.00528.2009. Epub 2009 Dec 23. Am J Physiol Renal Physiol. 2010. PMID: 20032117
Aldosterone induces CTGF in mesangial cells by activation of the glucocorticoid receptor.
Gauer S, Segitz V, Goppelt-Struebe M. Gauer S, et al. Nephrol Dial Transplant. 2007 Nov;22(11):3154-9. doi: 10.1093/ndt/gfm410. Epub 2007 Jun 30. Nephrol Dial Transplant. 2007. PMID: 17602195
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