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Use of the Rad51 promoter for targeted anti-cancer therapy.
Hine CM, Seluanov A, Gorbunova V. Hine CM, et al. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20810-5. doi: 10.1073/pnas.0807990106. Epub 2008 Dec 23. Proc Natl Acad Sci U S A. 2008. PMID: 19106292 Free PMC article.
Regulation of Rad51 promoter.
Hine CM, Li H, Xie L, Mao Z, Seluanov A, Gorbunova V. Hine CM, et al. Cell Cycle. 2014;13(13):2038-45. doi: 10.4161/cc.29016. Epub 2014 Apr 29. Cell Cycle. 2014. PMID: 24781030 Free PMC article.
L1 drives IFN in senescent cells and promotes age-associated inflammation.
De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM. De Cecco M, et al. Nature. 2019 Feb;566(7742):73-78. doi: 10.1038/s41586-018-0784-9. Epub 2019 Feb 6. Nature. 2019. PMID: 30728521 Free PMC article.
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