Gordon LB - Search Results

1

Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype.

Gabriel D, Gordon LB, Djabali K. Gabriel D, et al. Among authors: gordon lb. PLoS One. 2016 Dec 29;11(12):e0168988. doi: 10.1371/journal.pone.0168988. eCollection 2016. PLoS One. 2016. PMID: 28033363 Free PMC article.

2

Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.

Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, Erdos MR, Robbins CM, Moses TY, Berglund P, Dutra A, Pak E, Durkin S, Csoka AB, Boehnke M, Glover TW, Collins FS. Eriksson M, et al. Among authors: gordon lb. Nature. 2003 May 15;423(6937):293-8. doi: 10.1038/nature01629. Epub 2003 Apr 25. Nature. 2003. PMID: 12714972 Free article.

3

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome.

Goldman RD, Shumaker DK, Erdos MR, Eriksson M, Goldman AE, Gordon LB, Gruenbaum Y, Khuon S, Mendez M, Varga R, Collins FS. Goldman RD, et al. Among authors: gordon lb. Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8963-8. doi: 10.1073/pnas.0402943101. Epub 2004 Jun 7. Proc Natl Acad Sci U S A. 2004. PMID: 15184648 Free PMC article.

4

Reduced adiponectin and HDL cholesterol without elevated C-reactive protein: clues to the biology of premature atherosclerosis in Hutchinson-Gilford Progeria Syndrome.

Gordon LB, Harten IA, Patti ME, Lichtenstein AH. Gordon LB, et al. J Pediatr. 2005 Mar;146(3):336-41. doi: 10.1016/j.jpeds.2004.10.064. J Pediatr. 2005. PMID: 15756215

5

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome.

Capell BC, Erdos MR, Madigan JP, Fiordalisi JJ, Varga R, Conneely KN, Gordon LB, Der CJ, Cox AD, Collins FS. Capell BC, et al. Among authors: gordon lb. Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12879-84. doi: 10.1073/pnas.0506001102. Epub 2005 Aug 29. Proc Natl Acad Sci U S A. 2005. PMID: 16129833 Free PMC article.

6

Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.

McClintock D, Gordon LB, Djabali K. McClintock D, et al. Among authors: gordon lb. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2154-9. doi: 10.1073/pnas.0511133103. Epub 2006 Feb 6. Proc Natl Acad Sci U S A. 2006. PMID: 16461887 Free PMC article.

7

Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome.

Varga R, Eriksson M, Erdos MR, Olive M, Harten I, Kolodgie F, Capell BC, Cheng J, Faddah D, Perkins S, Avallone H, San H, Qu X, Ganesh S, Gordon LB, Virmani R, Wight TN, Nabel EG, Collins FS. Varga R, et al. Among authors: gordon lb. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3250-5. doi: 10.1073/pnas.0600012103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492728 Free PMC article.

8

Aggrecan expression is substantially and abnormally upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts.

Lemire JM, Patis C, Gordon LB, Sandy JD, Toole BP, Weiss AS. Lemire JM, et al. Among authors: gordon lb. Mech Ageing Dev. 2006 Aug;127(8):660-9. doi: 10.1016/j.mad.2006.03.004. Epub 2006 May 2. Mech Ageing Dev. 2006. PMID: 16650460

9

Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development.

Gordon LB, McCarten KM, Giobbie-Hurder A, Machan JT, Campbell SE, Berns SD, Kieran MW. Gordon LB, et al. Pediatrics. 2007 Oct;120(4):824-33. doi: 10.1542/peds.2007-1357. Pediatrics. 2007. PMID: 17908770

10

New approaches to progeria.

Kieran MW, Gordon L, Kleinman M. Kieran MW, et al. Pediatrics. 2007 Oct;120(4):834-41. doi: 10.1542/peds.2007-1356. Pediatrics. 2007. PMID: 17908771 Review.

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