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Genomic instability--an evolving hallmark of cancer.
Negrini S, Gorgoulis VG, Halazonetis TD. Negrini S, et al. Among authors: gorgoulis vg. Nat Rev Mol Cell Biol. 2010 Mar;11(3):220-8. doi: 10.1038/nrm2858. Nat Rev Mol Cell Biol. 2010. PMID: 20177397 Review.
Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1.
Zacharatos PV, Gorgoulis VG, Kotsinas A, Manolis EN, Liloglou T, Rassidakis AN, Kanavaros P, Field JD, Halazonetis T, Kittas C. Zacharatos PV, et al. Among authors: gorgoulis vg. Anticancer Res. 1999 Jan-Feb;19(1A):579-87. Anticancer Res. 1999. PMID: 10226602
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks.
Huyen Y, Zgheib O, Ditullio RA Jr, Gorgoulis VG, Zacharatos P, Petty TJ, Sheston EA, Mellert HS, Stavridi ES, Halazonetis TD. Huyen Y, et al. Among authors: gorgoulis vg. Nature. 2004 Nov 18;432(7015):406-11. doi: 10.1038/nature03114. Epub 2004 Nov 3. Nature. 2004. PMID: 15525939
Valosin-containing protein phosphorylation at Ser784 in response to DNA damage.
Livingstone M, Ruan H, Weiner J, Clauser KR, Strack P, Jin S, Williams A, Greulich H, Gardner J, Venere M, Mochan TA, DiTullio RA Jr, Moravcevic K, Gorgoulis VG, Burkhardt A, Halazonetis TD. Livingstone M, et al. Among authors: gorgoulis vg. Cancer Res. 2005 Sep 1;65(17):7533-40. doi: 10.1158/0008-5472.CAN-04-3729. Cancer Res. 2005. PMID: 16140914
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, Ørntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, Gorgoulis VG. Bartkova J, et al. Among authors: gorgoulis vg. Nature. 2006 Nov 30;444(7119):633-7. doi: 10.1038/nature05268. Nature. 2006. PMID: 17136093
Evaluation of claspin as a proliferation marker in human cancer and normal tissues.
Tsimaratou K, Kletsas D, Kastrinakis NG, Tsantoulis PK, Evangelou K, Sideridou M, Liontos M, Poulias I, Venere M, Salmas M, Kittas C, Halazonetis TD, Gorgoulis VG. Tsimaratou K, et al. Among authors: gorgoulis vg. J Pathol. 2007 Feb;211(3):331-9. doi: 10.1002/path.2095. J Pathol. 2007. PMID: 17152083
343 results