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584 results
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Scaffolding function of PAK in the PDK1-Akt pathway.
Higuchi M, Onishi K, Kikuchi C, Gotoh Y. Higuchi M, et al. Among authors: gotoh y. Nat Cell Biol. 2008 Nov;10(11):1356-64. doi: 10.1038/ncb1795. Epub 2008 Oct 19. Nat Cell Biol. 2008. PMID: 18931661
The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria.
Tsuruta F, Masuyama N, Gotoh Y. Tsuruta F, et al. Among authors: gotoh y. J Biol Chem. 2002 Apr 19;277(16):14040-7. doi: 10.1074/jbc.M108975200. Epub 2002 Feb 12. J Biol Chem. 2002. PMID: 11842081
Akt enhances Mdm2-mediated ubiquitination and degradation of p53.
Ogawara Y, Kishishita S, Obata T, Isazawa Y, Suzuki T, Tanaka K, Masuyama N, Gotoh Y. Ogawara Y, et al. Among authors: gotoh y. J Biol Chem. 2002 Jun 14;277(24):21843-50. doi: 10.1074/jbc.M109745200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923280
SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling.
Shinohara M, Terada Y, Iwamatsu A, Shinohara A, Mochizuki N, Higuchi M, Gotoh Y, Ihara S, Nagata S, Itoh H, Fukui Y, Jessberger R. Shinohara M, et al. Among authors: gotoh y. Nature. 2002 Apr 18;416(6882):759-63. doi: 10.1038/416759a. Nature. 2002. PMID: 11961559
Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes.
Fujishiro M, Gotoh Y, Katagiri H, Sakoda H, Ogihara T, Anai M, Onishi Y, Ono H, Abe M, Shojima N, Fukushima Y, Kikuchi M, Oka Y, Asano T. Fujishiro M, et al. Among authors: gotoh y. Mol Endocrinol. 2003 Mar;17(3):487-97. doi: 10.1210/me.2002-0131. Epub 2002 Dec 5. Mol Endocrinol. 2003. PMID: 12554784
Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade.
Suzawa M, Takada I, Yanagisawa J, Ohtake F, Ogawa S, Yamauchi T, Kadowaki T, Takeuchi Y, Shibuya H, Gotoh Y, Matsumoto K, Kato S. Suzawa M, et al. Among authors: gotoh y. Nat Cell Biol. 2003 Mar;5(3):224-30. doi: 10.1038/ncb942. Nat Cell Biol. 2003. PMID: 12598905 Retracted.
Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions.
Katome T, Obata T, Matsushima R, Masuyama N, Cantley LC, Gotoh Y, Kishi K, Shiota H, Ebina Y. Katome T, et al. Among authors: gotoh y. J Biol Chem. 2003 Jul 25;278(30):28312-23. doi: 10.1074/jbc.M302094200. Epub 2003 May 6. J Biol Chem. 2003. PMID: 12734182
Differing roles of Akt and serum- and glucocorticoid-regulated kinase in glucose metabolism, DNA synthesis, and oncogenic activity.
Sakoda H, Gotoh Y, Katagiri H, Kurokawa M, Ono H, Onishi Y, Anai M, Ogihara T, Fujishiro M, Fukushima Y, Abe M, Shojima N, Kikuchi M, Oka Y, Hirai H, Asano T. Sakoda H, et al. Among authors: gotoh y. J Biol Chem. 2003 Jul 11;278(28):25802-7. doi: 10.1074/jbc.M301127200. Epub 2003 May 6. J Biol Chem. 2003. PMID: 12734207
The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells.
Higuchi M, Onishi K, Masuyama N, Gotoh Y. Higuchi M, et al. Among authors: gotoh y. Genes Cells. 2003 Aug;8(8):657-69. doi: 10.1046/j.1365-2443.2003.00663.x. Genes Cells. 2003. PMID: 12875651
JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins.
Tsuruta F, Sunayama J, Mori Y, Hattori S, Shimizu S, Tsujimoto Y, Yoshioka K, Masuyama N, Gotoh Y. Tsuruta F, et al. Among authors: gotoh y. EMBO J. 2004 Apr 21;23(8):1889-99. doi: 10.1038/sj.emboj.7600194. Epub 2004 Apr 8. EMBO J. 2004. PMID: 15071501 Free PMC article.
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