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Rational parameters for antibiotic therapy in patients with cystic fibrosis.
Govan JR, Doherty C, Glass S. Govan JR, et al. Infection. 1987 Jul-Aug;15(4):300-7. doi: 10.1007/BF01644142. Infection. 1987. PMID: 3117704 Review.
Covalent dimer species of beta-defensin Defr1 display potent antimicrobial activity against multidrug-resistant bacterial pathogens.
Taylor K, McCullough B, Clarke DJ, Langley RJ, Pechenick T, Hill A, Campopiano DJ, Barran PE, Dorin JR, Govan JR. Taylor K, et al. Antimicrob Agents Chemother. 2007 May;51(5):1719-24. doi: 10.1128/AAC.01531-06. Epub 2007 Mar 12. Antimicrob Agents Chemother. 2007. PMID: 17353239 Free PMC article.
Cathelicidin host defence peptide augments clearance of pulmonary Pseudomonas aeruginosa infection by its influence on neutrophil function in vivo.
Beaumont PE, McHugh B, Gwyer Findlay E, Mackellar A, Mackenzie KJ, Gallo RL, Govan JR, Simpson AJ, Davidson DJ. Beaumont PE, et al. Among authors: govan jr. PLoS One. 2014 Jun 2;9(6):e99029. doi: 10.1371/journal.pone.0099029. eCollection 2014. PLoS One. 2014. PMID: 24887410 Free PMC article.
Hypermutability in environmental Pseudomonas aeruginosa and in populations causing pulmonary infection in individuals with cystic fibrosis.
Kenna DT, Doherty CJ, Foweraker J, Macaskill L, Barcus VA, Govan JRW. Kenna DT, et al. Microbiology. 2007 Jun;153(Pt 6):1852-1859. doi: 10.1099/mic.0.2006/005082-0. Microbiology. 2007. PMID: 17526842
Prospective surveillance for Pseudomonas aeruginosa cross-infection at a cystic fibrosis center.
Jones AM, Dodd ME, Govan JR, Doherty CJ, Smith CM, Isalska BJ, Webb AK. Jones AM, et al. Am J Respir Crit Care Med. 2005 Feb 1;171(3):257-60. doi: 10.1164/rccm.200404-513OC. Epub 2004 Nov 12. Am J Respir Crit Care Med. 2005. PMID: 15542795
A Randomized Controlled Trial of Atorvastatin in Patients With Bronchiectasis Infected With Pseudomonas Aeruginosa: A Proof of Concept Study.
Bedi P, Chalmers JD, Graham C, Clarke A, Donaldson S, Doherty C, Govan JRW, Davidson DJ, Rossi AG, Hill AT. Bedi P, et al. Among authors: govan jrw. Chest. 2017 Aug;152(2):368-378. doi: 10.1016/j.chest.2017.05.017. Epub 2017 May 26. Chest. 2017. PMID: 28554732 Free article. Clinical Trial.
A randomized controlled trial of nebulized gentamicin in non-cystic fibrosis bronchiectasis.
Murray MP, Govan JR, Doherty CJ, Simpson AJ, Wilkinson TS, Chalmers JD, Greening AP, Haslett C, Hill AT. Murray MP, et al. Am J Respir Crit Care Med. 2011 Feb 15;183(4):491-9. doi: 10.1164/rccm.201005-0756OC. Epub 2010 Sep 24. Am J Respir Crit Care Med. 2011. PMID: 20870753 Clinical Trial.
Lung pathology in response to repeated exposure to Staphylococcus aureus in congenic residual function cystic fibrosis mice does not increase in response to decreased CFTR levels or increased bacterial load.
Davidson DJ, Webb S, Teague P, Govan JR, Dorin JR. Davidson DJ, et al. Pathobiology. 2004;71(3):152-8. doi: 10.1159/000076470. Pathobiology. 2004. PMID: 15051928
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