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Glucocorticoid receptor isoform-specific regulation of development, circadian rhythm, and inflammation in mice.
FASEB J. 2018 Oct;32(10):5258-5271. doi: 10.1096/fj.201701153R. Epub 2018 Apr 19.
FASEB J. 2018.
PMID: 29672221
Free PMC article.
We have generated knockin mice that exclusively express the most active receptor isoform, GR-C3. GR-C3 knockin mice die at birth due to respiratory distress. Microarray analysis of fibroblasts from wild-type and GR-C3 mice indicated that …
We have generated knockin mice that exclusively express the most active receptor isoform, GR-C3. GR-C3 knockin m …
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