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Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.
Marenholz I, Nickel R, Rüschendorf F, Schulz F, Esparza-Gordillo J, Kerscher T, Grüber C, Lau S, Worm M, Keil T, Kurek M, Zaluga E, Wahn U, Lee YA. Marenholz I, et al. Among authors: gruber c. J Allergy Clin Immunol. 2006 Oct;118(4):866-71. doi: 10.1016/j.jaci.2006.07.026. Epub 2006 Sep 1. J Allergy Clin Immunol. 2006. PMID: 17030239
The development of childhood asthma: lessons from the German Multicentre Allergy Study (MAS).
Lau S, Nickel R, Niggemann B, Grüber C, Sommerfeld C, Illi S, Kulig M, Forster J, Wahn U, Groeger M, Zepp F, Kamin W, Bieber I, Tacke U, Wahn V, Bauer CP, Bergmann R, von Mutius E; MAS Group. Lau S, et al. Among authors: gruber c. Paediatr Respir Rev. 2002 Sep;3(3):265-72. doi: 10.1016/s1526-0542(02)00189-6. Paediatr Respir Rev. 2002. PMID: 12376064 Review.
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