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Rogaratinib: A potent and selective pan-FGFR inhibitor with broad antitumor activity in FGFR-overexpressing preclinical cancer models.
Grünewald S, Politz O, Bender S, Héroult M, Lustig K, Thuss U, Kneip C, Kopitz C, Zopf D, Collin MP, Boemer U, Ince S, Ellinghaus P, Mumberg D, Hess-Stumpp H, Ziegelbauer K. Grünewald S, et al. Int J Cancer. 2019 Sep 1;145(5):1346-1357. doi: 10.1002/ijc.32224. Epub 2019 Mar 13. Int J Cancer. 2019. PMID: 30807645 Free PMC article.
Discovery of Rogaratinib (BAY 1163877): a pan-FGFR Inhibitor.
Collin MP, Lobell M, Hübsch W, Brohm D, Schirok H, Jautelat R, Lustig K, Bömer U, Vöhringer V, Héroult M, Grünewald S, Hess-Stumpp H. Collin MP, et al. Among authors: grunewald s. ChemMedChem. 2018 Mar 6;13(5):437-445. doi: 10.1002/cmdc.201700718. Epub 2018 Feb 16. ChemMedChem. 2018. PMID: 29451369
Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance.
Quanz M, Bender E, Kopitz C, Grünewald S, Schlicker A, Schwede W, Eheim A, Toschi L, Neuhaus R, Richter C, Toedling J, Merz C, Lesche R, Kamburov A, Siebeneicher H, Bauser M, Hägebarth A. Quanz M, et al. Among authors: grunewald s. Mol Cancer Ther. 2018 Nov;17(11):2285-2296. doi: 10.1158/1535-7163.MCT-17-1253. Epub 2018 Aug 16. Mol Cancer Ther. 2018. PMID: 30115664
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.
Vriens K, Christen S, Parik S, Broekaert D, Yoshinaga K, Talebi A, Dehairs J, Escalona-Noguero C, Schmieder R, Cornfield T, Charlton C, Romero-Pérez L, Rossi M, Rinaldi G, Orth MF, Boon R, Kerstens A, Kwan SY, Faubert B, Méndez-Lucas A, Kopitz CC, Chen T, Fernandez-Garcia J, Duarte JAG, Schmitz AA, Steigemann P, Najimi M, Hägebarth A, Van Ginderachter JA, Sokal E, Gotoh N, Wong KK, Verfaillie C, Derua R, Munck S, Yuneva M, Beretta L, DeBerardinis RJ, Swinnen JV, Hodson L, Cassiman D, Verslype C, Christian S, Grünewald S, Grünewald TGP, Fendt SM. Vriens K, et al. Among authors: grunewald s, grunewald tgp. Nature. 2019 Feb;566(7744):403-406. doi: 10.1038/s41586-019-0904-1. Epub 2019 Feb 6. Nature. 2019. PMID: 30728499 Free PMC article.
Identification of regulated genes during permanent focal cerebral ischaemia: characterization of the protein kinase 9b5/MARKL1/MARK4.
Schneider A, Laage R, von Ahsen O, Fischer A, Rossner M, Scheek S, Grünewald S, Kuner R, Weber D, Krüger C, Klaussner B, Götz B, Hiemisch H, Newrzella D, Martin-Villalba A, Bach A, Schwaninger M. Schneider A, et al. Among authors: grunewald s. J Neurochem. 2004 Mar;88(5):1114-26. doi: 10.1046/j.1471-4159.2003.02228.x. J Neurochem. 2004. PMID: 15009667 Free article.
Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor.
Maurer MH, Grünewald S, Gassler N, Rossner M, Propst F, Würz R, Weber D, Kuner T, Kuschinsky W, Schneider A. Maurer MH, et al. Among authors: grunewald s. J Neurochem. 2004 Nov;91(4):1007-17. doi: 10.1111/j.1471-4159.2004.02799.x. J Neurochem. 2004. PMID: 15525354 Free article.
Monitoring regulated protein-protein interactions using split TEV.
Wehr MC, Laage R, Bolz U, Fischer TM, Grünewald S, Scheek S, Bach A, Nave KA, Rossner MJ. Wehr MC, et al. Among authors: grunewald s. Nat Methods. 2006 Dec;3(12):985-93. doi: 10.1038/nmeth967. Epub 2006 Oct 29. Nat Methods. 2006. PMID: 17072307
Role of heteromer formation in GABAB receptor function.
Kuner R, Köhr G, Grünewald S, Eisenhardt G, Bach A, Kornau HC. Kuner R, et al. Among authors: grunewald s. Science. 1999 Jan 1;283(5398):74-7. doi: 10.1126/science.283.5398.74. Science. 1999. PMID: 9872744
383 results