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Page 1
Pancreatic cancer.
Roth S, Apte M, Balachandran VP, Biffi G, Conroy T, Cukierman E, Dotan E, Esposito I, Grünwald BT, Klauß M, Klein AP, Malats N, O Reilly EM, Pishvaian MJ, Real FX, Saur D, Siveke JT, Michalski CW. Roth S, et al. Among authors: grunwald bt. Nat Rev Dis Primers. 2026 May 7;12(1):23. doi: 10.1038/s41572-026-00699-6. Nat Rev Dis Primers. 2026. PMID: 42098138 Review.
Development and Validation of a Computational Histology Artificial Intelligence-Powered Predictive Biomarker for Selection of Chemotherapy in Advanced Pancreatic Cancer.
Hendifar AE, Krishna V, Krishna V, Zhang H, Tarsode A, Nimgaonkar V, Smith K, Abdilleh K, Sonawane S, Neema A, Tiu E, Larson BK, Kazarov V, Moshayedi N, Hutchinson S, Bevacqua D, Doss S, Alvarez A, Watson D, Abuzeid WM, Grünwald BT, Noel M, Samdani R, Keith D, Sears RC, Sohal D, Fountzilas C, O'Kane GM, Grant RC, Osipov A, Collisson EA, Kiedrowski LA, Royce TJ, Joshi AR, Singhi AD, Knox JJ. Hendifar AE, et al. Among authors: grunwald bt. J Clin Oncol. 2026 Feb 11:JCO2502199. doi: 10.1200/JCO-25-02199. Online ahead of print. J Clin Oncol. 2026. PMID: 41671529
Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma.
Peng J, Yang J, Antonopoulou G, Fang R, Adhikari B, Vogt M, Wolf E, Sun C, Du S, Godfrey L, Gupta A, Trajkovic-Arsic M, Teichmann N, Grünwald BT, Krebs N, Steiger K, Mogler C, Althoff K, Wang X, Giglio G, Liffers ST, Savvatakis K, Braren R, Lawlor RT, Scarpa A, Behrens D, Lang KS, Cheung PF, Siveke JT. Peng J, et al. Among authors: grunwald bt. Nat Commun. 2026 Feb 6;17(1):1476. doi: 10.1038/s41467-026-69013-y. Nat Commun. 2026. PMID: 41651844 Free PMC article.
Transcription factor switching drives subtype-specific pancreatic cancer.
Rao SV, Young L, Cheeseman D, Flynn S, Krebs N, Couturier DL, Mack S, Brais R, Temple J, Smith A, Papachristou E, Pelicano C, Chilamakuri CSR, Herka K, Baba H, Farah L, Cheung PF, Siveke J, Guerrier S, Insolia L, Gill M, Archer Goode E, Kupczak S, Cheng Y, Borsari G, Jodrell D, D'Santos C, Russell A, Grünwald BT, Serrao E, Chernukhin I, Carroll JS. Rao SV, et al. Among authors: grunwald bt. Nat Genet. 2025 Dec;57(12):3016-3026. doi: 10.1038/s41588-025-02389-7. Epub 2025 Oct 30. Nat Genet. 2025. PMID: 41168397 Free PMC article.
Tumour tissue: heterogeneous, but not disordered.
Grünwald BT, Khokha R. Grünwald BT, et al. Nat Rev Cancer. 2025 Nov;25(11):821-822. doi: 10.1038/s41568-025-00852-5. Nat Rev Cancer. 2025. PMID: 40659926 No abstract available.
Whole genome and transcriptome profiling in advanced pancreatic cancer patients on the COMPASS trial.
Knox JJ, Jang GH, Grant RC, Zhang A, Ma L, Elimova E, Jang R, Moore M, Biagi J, Tehfe M, Ramjeesingh R, Tsang ES, Holter S, Ramotar S, Hutchinson S, Liang SB, Lungu IM, Moura S, Wang Y, Perera S, Chan-Seng-Yue M, Monajemzadeh M, Aung K, Prince R, Romero JM, Fuentes-Antras J, Gonzalez Conchas GA, Picardo S, Gonzalez R, Ghai S, Khalili K, Kyoung Kim T, Ng K, Bartlett J, Pugh TJ, Kalimuthu SN, Fischer SE, Wilson JM, Dodd A, Zogopoulos G, Grünwald BT, Notta F, Gallinger S, O'Kane GM. Knox JJ, et al. Among authors: grunwald bt. Nat Commun. 2025 Jul 1;16(1):5919. doi: 10.1038/s41467-025-60808-z. Nat Commun. 2025. PMID: 40593593 Free PMC article.
Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer.
Klein L, Tu M, Krebs N, Urbach L, Grimm D, Latif MU, Penz F, Blandau A, Wu X, Samuel RD, Küffer S, Wegwitz F, Chan N, Aliar K, Vyas F, Kishore U, Hessmann E, Trumpp A, Espinet E, Papantonis A, Khokha R, Ellenrieder V, Grünwald BT, Singh SK. Klein L, et al. Among authors: grunwald bt. Nat Commun. 2025 Jan 6;16(1):335. doi: 10.1038/s41467-024-55330-7. Nat Commun. 2025. PMID: 39762215 Free PMC article.
40 results