Grüschow S - Search Results

1

Isolation and structure elucidation of Chlorofusin, a novel p53-MDM2 antagonist from a Fusarium sp.

Duncan SJ, Grüschow S, Williams DH, McNicholas C, Purewal R, Hajek M, Gerlitz M, Martin S, Wrigley SK, Moore M. Duncan SJ, et al. Among authors: gruschow s. J Am Chem Soc. 2001 Jan 31;123(4):554-60. doi: 10.1021/ja002940p. J Am Chem Soc. 2001. PMID: 11456567

2

Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation.

Jeong JC, Srinivasan A, Grüschow S, Bach H, Sherman DH, Dordick JS. Jeong JC, et al. Among authors: gruschow s. J Am Chem Soc. 2005 Jan 12;127(1):64-5. doi: 10.1021/ja0441559. J Am Chem Soc. 2005. PMID: 15631450

3

Gene expression enabling synthetic diversification of natural products: chemogenetic generation of pacidamycin analogs.

Deb Roy A, Grüschow S, Cairns N, Goss RJ. Deb Roy A, et al. Among authors: gruschow s. J Am Chem Soc. 2010 Sep 8;132(35):12243-5. doi: 10.1021/ja1060406. J Am Chem Soc. 2010. PMID: 20712319

4

Biogenesis of the unique 4',5'-dehydronucleoside of the uridyl peptide antibiotic pacidamycin.

Ragab AE, Grüschow S, Tromans DR, Goss RJ. Ragab AE, et al. Among authors: gruschow s. J Am Chem Soc. 2011 Oct 5;133(39):15288-91. doi: 10.1021/ja206163j. Epub 2011 Sep 12. J Am Chem Soc. 2011. PMID: 21861518

5

Hydroxyquinone O-methylation in mitomycin biosynthesis.

Grüschow S, Chang LC, Mao Y, Sherman DH. Grüschow S, et al. J Am Chem Soc. 2007 May 23;129(20):6470-6. doi: 10.1021/ja0700193. Epub 2007 Apr 27. J Am Chem Soc. 2007. PMID: 17461583

6

Molecular analysis of the role of tyrosine 224 in the active site of Streptomyces coelicolor RppA, a bacterial type III polyketide synthase.

Li S, Grüschow S, Dordick JS, Sherman DH. Li S, et al. Among authors: gruschow s. J Biol Chem. 2007 Apr 27;282(17):12765-72. doi: 10.1074/jbc.M700393200. Epub 2007 Mar 1. J Biol Chem. 2007. PMID: 17331946 Free article.

7

Substrate profile analysis and ACP-mediated acyl transfer in Streptomyces coelicolor Type III polyketide synthases.

Grüschow S, Buchholz TJ, Seufert W, Dordick JS, Sherman DH. Grüschow S, et al. Chembiochem. 2007 May 25;8(8):863-8. doi: 10.1002/cbic.200700026. Chembiochem. 2007. PMID: 17440908 Free article. No abstract available.

8

Enzymatic assembly of the bis-indole core of rebeccamycin.

Nishizawa T, Grüschow S, Jayamaha DH, Nishizawa-Harada C, Sherman DH. Nishizawa T, et al. Among authors: gruschow s. J Am Chem Soc. 2006 Jan 25;128(3):724-5. doi: 10.1021/ja056749x. J Am Chem Soc. 2006. PMID: 16417354

9

Synthesis of potential early-stage intermediates in the biosynthesis of FR900482 and mitomycin C.

Chamberland S, Grüschow S, Sherman DH, Williams RM. Chamberland S, et al. Among authors: gruschow s. Org Lett. 2009 Feb 19;11(4):791-4. doi: 10.1021/ol802631c. Org Lett. 2009. PMID: 19161340 Free PMC article.

10

Structural characterization of the mitomycin 7-O-methyltransferase.

Singh S, Chang A, Goff RD, Bingman CA, Grüschow S, Sherman DH, Phillips GN Jr, Thorson JS. Singh S, et al. Among authors: gruschow s. Proteins. 2011 Jul;79(7):2181-8. doi: 10.1002/prot.23040. Epub 2011 May 2. Proteins. 2011. PMID: 21538548 Free PMC article.

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