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Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3.
Jacquemin P, Durviaux SM, Jensen J, Godfraind C, Gradwohl G, Guillemot F, Madsen OD, Carmeliet P, Dewerchin M, Collen D, Rousseau GG, Lemaigre FP. Jacquemin P, et al. Among authors: gradwohl g. Mol Cell Biol. 2000 Jun;20(12):4445-54. doi: 10.1128/MCB.20.12.4445-4454.2000. Mol Cell Biol. 2000. PMID: 10825208 Free PMC article.
Development of the endocrine pancreas.
Gradwohl G. Gradwohl G. Diabetes Metab. 2006 Dec;32(5 Pt 2):532-3. doi: 10.1016/s1262-3636(06)72807-5. Diabetes Metab. 2006. PMID: 17130813
IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.
Mellitzer G, Bonné S, Luco RF, Van De Casteele M, Lenne-Samuel N, Collombat P, Mansouri A, Lee J, Lan M, Pipeleers D, Nielsen FC, Ferrer J, Gradwohl G, Heimberg H. Mellitzer G, et al. Among authors: gradwohl g. EMBO J. 2006 Mar 22;25(6):1344-52. doi: 10.1038/sj.emboj.7601011. Epub 2006 Mar 2. EMBO J. 2006. PMID: 16511571 Free PMC article.
Opposing actions of Arx and Pax4 in endocrine pancreas development.
Collombat P, Mansouri A, Hecksher-Sorensen J, Serup P, Krull J, Gradwohl G, Gruss P. Collombat P, et al. Among authors: gradwohl g. Genes Dev. 2003 Oct 15;17(20):2591-603. doi: 10.1101/gad.269003. Genes Dev. 2003. PMID: 14561778 Free PMC article.
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