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Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models.
Härmä V, Knuuttila M, Virtanen J, Mirtti T, Kohonen P, Kovanen P, Happonen A, Kaewphan S, Ahonen I, Kallioniemi O, Grafström R, Lötjönen J, Nees M. Härmä V, et al. Among authors: grafstrom r. Oncogene. 2012 Apr 19;31(16):2075-89. doi: 10.1038/onc.2011.396. Epub 2011 Sep 26. Oncogene. 2012. PMID: 21996742 Free PMC article.
Reply to: Prospects and challenges for FAIR toxicogenomics data.
Grafström R, Haase A, Kohonen P, Jeliazkova N, Nymark P. Grafström R, et al. Nat Nanotechnol. 2022 Jan;17(1):19-20. doi: 10.1038/s41565-021-01050-8. Epub 2021 Dec 23. Nat Nanotechnol. 2022. PMID: 34949776 No abstract available.
Transcriptomics in Toxicogenomics, Part III: Data Modelling for Risk Assessment.
Serra A, Fratello M, Cattelani L, Liampa I, Melagraki G, Kohonen P, Nymark P, Federico A, Kinaret PAS, Jagiello K, Ha MK, Choi JS, Sanabria N, Gulumian M, Puzyn T, Yoon TH, Sarimveis H, Grafström R, Afantitis A, Greco D. Serra A, et al. Among authors: grafstrom r. Nanomaterials (Basel). 2020 Apr 8;10(4):708. doi: 10.3390/nano10040708. Nanomaterials (Basel). 2020. PMID: 32276469 Free PMC article. Review.
Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects.
Kinaret PAS, Serra A, Federico A, Kohonen P, Nymark P, Liampa I, Ha MK, Choi JS, Jagiello K, Sanabria N, Melagraki G, Cattelani L, Fratello M, Sarimveis H, Afantitis A, Yoon TH, Gulumian M, Grafström R, Puzyn T, Greco D. Kinaret PAS, et al. Among authors: grafstrom r. Nanomaterials (Basel). 2020 Apr 15;10(4):750. doi: 10.3390/nano10040750. Nanomaterials (Basel). 2020. PMID: 32326418 Free PMC article. Review.
Transcriptomics in Toxicogenomics, Part II: Preprocessing and Differential Expression Analysis for High Quality Data.
Federico A, Serra A, Ha MK, Kohonen P, Choi JS, Liampa I, Nymark P, Sanabria N, Cattelani L, Fratello M, Kinaret PAS, Jagiello K, Puzyn T, Melagraki G, Gulumian M, Afantitis A, Sarimveis H, Yoon TH, Grafström R, Greco D. Federico A, et al. Among authors: grafstrom r. Nanomaterials (Basel). 2020 May 8;10(5):903. doi: 10.3390/nano10050903. Nanomaterials (Basel). 2020. PMID: 32397130 Free PMC article. Review.
Cancer biology, toxicology and alternative methods development go hand-in-hand.
Kohonen P, Ceder R, Smit I, Hongisto V, Myatt G, Hardy B, Spjuth O, Grafström R. Kohonen P, et al. Among authors: grafstrom r. Basic Clin Pharmacol Toxicol. 2014 Jul;115(1):50-8. doi: 10.1111/bcpt.12257. Epub 2014 May 23. Basic Clin Pharmacol Toxicol. 2014. PMID: 24779563 Free article. Review.
Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices.
Nymark P, Bakker M, Dekkers S, Franken R, Fransman W, García-Bilbao A, Greco D, Gulumian M, Hadrup N, Halappanavar S, Hongisto V, Hougaard KS, Jensen KA, Kohonen P, Koivisto AJ, Dal Maso M, Oosterwijk T, Poikkimäki M, Rodriguez-Llopis I, Stierum R, Sørli JB, Grafström R. Nymark P, et al. Among authors: grafstrom r. Small. 2020 Feb;16(6):e1904749. doi: 10.1002/smll.201904749. Epub 2020 Jan 8. Small. 2020. PMID: 31913582 Review.
NanoSolveIT Project: Driving nanoinformatics research to develop innovative and integrated tools for in silico nanosafety assessment.
Afantitis A, Melagraki G, Isigonis P, Tsoumanis A, Varsou DD, Valsami-Jones E, Papadiamantis A, Ellis LA, Sarimveis H, Doganis P, Karatzas P, Tsiros P, Liampa I, Lobaskin V, Greco D, Serra A, Kinaret PAS, Saarimäki LA, Grafström R, Kohonen P, Nymark P, Willighagen E, Puzyn T, Rybinska-Fryca A, Lyubartsev A, Alstrup Jensen K, Brandenburg JG, Lofts S, Svendsen C, Harrison S, Maier D, Tamm K, Jänes J, Sikk L, Dusinska M, Longhin E, Rundén-Pran E, Mariussen E, El Yamani N, Unger W, Radnik J, Tropsha A, Cohen Y, Leszczynski J, Ogilvie Hendren C, Wiesner M, Winkler D, Suzuki N, Yoon TH, Choi JS, Sanabria N, Gulumian M, Lynch I. Afantitis A, et al. Among authors: grafstrom r. Comput Struct Biotechnol J. 2020 Mar 7;18:583-602. doi: 10.1016/j.csbj.2020.02.023. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 32226594 Free PMC article. Review.
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