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Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
Nat Genet. 2015 Dec;47(12):1457-1464. doi: 10.1038/ng.3434. Epub 2015 Oct 26.
Nat Genet. 2015.
PMID: 26502338
Free PMC article.
Association of the co-stimulator OX40L with systemic lupus erythematosus.
Manku H, Graham DS, Vyse TJ.
Manku H, et al.
J Mol Med (Berl). 2009 Mar;87(3):229-34. doi: 10.1007/s00109-008-0431-2. Epub 2008 Dec 16.
J Mol Med (Berl). 2009.
PMID: 19083191
Review.
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Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE.
Morris DL, Graham RR, Erwig LP, Gaffney PM, Moser KL, Behrens TW, Vyse TJ, Graham DS.
Morris DL, et al.
Genes Immun. 2009 Jul;10(5):404-13. doi: 10.1038/gene.2009.17. Epub 2009 Apr 30.
Genes Immun. 2009.
PMID: 19404301
Free PMC article.
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FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity.
Fanciulli M, Norsworthy PJ, Petretto E, Dong R, Harper L, Kamesh L, Heward JM, Gough SC, de Smith A, Blakemore AI, Froguel P, Owen CJ, Pearce SH, Teixeira L, Guillevin L, Graham DS, Pusey CD, Cook HT, Vyse TJ, Aitman TJ.
Fanciulli M, et al.
Nat Genet. 2007 Jun;39(6):721-3. doi: 10.1038/ng2046. Epub 2007 May 21.
Nat Genet. 2007.
PMID: 17529978
Free PMC article.
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The heritability and genetics of complement C3 expression in UK SLE families.
Rhodes B, Hunnangkul S, Morris DL, Hsaio LC, Graham DS, Nitsch D, Whittaker JC, Vyse TJ.
Rhodes B, et al.
Genes Immun. 2009 Jul;10(5):525-30. doi: 10.1038/gene.2009.23. Epub 2009 Apr 23.
Genes Immun. 2009.
PMID: 19387462
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Association analysis of the R620W polymorphism of protein tyrosine phosphatase PTPN22 in systemic lupus erythematosus families: increased T allele frequency in systemic lupus erythematosus patients with autoimmune thyroid disease.
Wu H, Cantor RM, Graham DS, Lingren CM, Farwell L, Jager PL, Bottini N, Grossman JM, Wallace DJ, Hahn BH, Julkunen H, Hebert LA, Rovin BH, Birmingham DJ, Rioux JD, Yu CY, Kere J, Vyse TJ, Tsao BP.
Wu H, et al.
Arthritis Rheum. 2005 Aug;52(8):2396-402. doi: 10.1002/art.21223.
Arthritis Rheum. 2005.
PMID: 16052563
Free article.
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