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The chemokine ESkine/CCL27 displays novel modes of intracrine and paracrine function.
Gortz A, Nibbs RJ, McLean P, Jarmin D, Lambie W, Baird JW, Graham GJ. Gortz A, et al. J Immunol. 2002 Aug 1;169(3):1387-94. doi: 10.4049/jimmunol.169.3.1387. J Immunol. 2002. PMID: 12133963
CCL27/PESKY: a novel paradigm for chemokine function.
Nibbs RJ, Graham GJ. Nibbs RJ, et al. Expert Opin Biol Ther. 2003 Feb;3(1):15-22. doi: 10.1517/14712598.3.1.15. Expert Opin Biol Ther. 2003. PMID: 12718728 Review.
Purification and biochemical characterization of the D6 chemokine receptor.
Blackburn PE, Simpson CV, Nibbs RJ, O'Hara M, Booth R, Poulos J, Isaacs NW, Graham GJ. Blackburn PE, et al. Biochem J. 2004 Apr 15;379(Pt 2):263-72. doi: 10.1042/BJ20031266. Biochem J. 2004. PMID: 14723600 Free PMC article.
The chemokine receptor D6 constitutively traffics to and from the cell surface to internalize and degrade chemokines.
Weber M, Blair E, Simpson CV, O'Hara M, Blackburn PE, Rot A, Graham GJ, Nibbs RJ. Weber M, et al. Mol Biol Cell. 2004 May;15(5):2492-508. doi: 10.1091/mbc.e03-09-0634. Epub 2004 Mar 5. Mol Biol Cell. 2004. PMID: 15004236 Free PMC article.
The chemokine receptor D6 limits the inflammatory response in vivo.
Jamieson T, Cook DN, Nibbs RJ, Rot A, Nixon C, McLean P, Alcami A, Lira SA, Wiekowski M, Graham GJ. Jamieson T, et al. Nat Immunol. 2005 Apr;6(4):403-11. doi: 10.1038/ni1182. Epub 2005 Mar 6. Nat Immunol. 2005. PMID: 15750596
Cutting edge: the silent chemokine receptor D6 is required for generating T cell responses that mediate experimental autoimmune encephalomyelitis.
Liu L, Graham GJ, Damodaran A, Hu T, Lira SA, Sasse M, Canasto-Chibuque C, Cook DN, Ransohoff RM. Liu L, et al. J Immunol. 2006 Jul 1;177(1):17-21. doi: 10.4049/jimmunol.177.1.17. J Immunol. 2006. PMID: 16785491
Chemokine scavenging by D6: a movable feast?
Graham GJ, McKimmie CS. Graham GJ, et al. Trends Immunol. 2006 Aug;27(8):381-6. doi: 10.1016/ Epub 2006 Jun 30. Trends Immunol. 2006. PMID: 16814608
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