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Age-related epithelial defects limit thymic function and regeneration.
Kousa AI, Jahn L, Zhao K, Flores AE, Acenas D 2nd, Lederer E, Argyropoulos KV, Lemarquis AL, Granadier D, Cooper K, D'Andrea M, Sheridan JM, Tsai J, Sikkema L, Lazrak A, Nichols K, Lee N, Ghale R, Malard F, Andrlova H, Velardi E, Youssef S, Burgos da Silva M, Docampo M, Sharma R, Mazutis L, Wimmer VC, Rogers KL, DeWolf S, Gipson B, Gomes ALC, Setty M, Pe'er D, Hale L, Manley NR, Gray DHD, van den Brink MRM, Dudakov JA. Kousa AI, et al. Among authors: granadier d. Nat Immunol. 2024 Sep;25(9):1593-1606. doi: 10.1038/s41590-024-01915-9. Epub 2024 Aug 7. Nat Immunol. 2024. PMID: 39112630 Free PMC article.
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.
Chung J, Ebens CL, Perkey E, Radojcic V, Koch U, Scarpellino L, Tong A, Allen F, Wood S, Feng J, Friedman A, Granadier D, Tran IT, Chai Q, Onder L, Yan M, Reddy P, Blazar BR, Huang AY, Brennan TV, Bishop DK, Ludewig B, Siebel CW, Radtke F, Luther SA, Maillard I. Chung J, et al. Among authors: granadier d. J Clin Invest. 2017 Apr 3;127(4):1574-1588. doi: 10.1172/JCI89535. Epub 2017 Mar 20. J Clin Invest. 2017. PMID: 28319044 Free PMC article.
GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.
Perkey E, Maurice De Sousa D, Carrington L, Chung J, Dils A, Granadier D, Koch U, Radtke F, Ludewig B, Blazar BR, Siebel CW, Brennan TV, Nolz J, Labrecque N, Maillard I. Perkey E, et al. Among authors: granadier d. J Immunol. 2020 Mar 15;204(6):1674-1688. doi: 10.4049/jimmunol.1901194. Epub 2020 Feb 14. J Immunol. 2020. PMID: 32060138 Free PMC article.