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1999 1
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2020 3
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12 results

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Page 1
Excessive O-GlcNAcylation Causes Heart Failure and Sudden Death.
Umapathi P, Mesubi OO, Banerjee PS, Abrol N, Wang Q, Luczak ED, Wu Y, Granger JM, Wei AC, Reyes Gaido OE, Florea L, Talbot CC Jr, Hart GW, Zachara NE, Anderson ME. Umapathi P, et al. Among authors: granger jm. Circulation. 2021 Apr 27;143(17):1687-1703. doi: 10.1161/CIRCULATIONAHA.120.051911. Epub 2021 Feb 17. Circulation. 2021. PMID: 33593071 Free PMC article.
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor.
Reyes Gaido OE, Pavlaki N, Granger JM, Mesubi OO, Liu B, Lin BL, Long A, Walker D, Mayourian J, Schole KL, Terrillion CE, Nkashama LJ, Hulsurkar MM, Dorn LE, Ferrero KM, Huganir RL, Müller FU, Wehrens XHT, Liu JO, Luczak ED, Bezzerides VJ, Anderson ME. Reyes Gaido OE, et al. Among authors: granger jm. Sci Transl Med. 2023 Jun 21;15(701):eabq7839. doi: 10.1126/scitranslmed.abq7839. Epub 2023 Jun 21. Sci Transl Med. 2023. PMID: 37343080 Free PMC article.
CaMKII exacerbates heart failure progression by activating class I HDACs.
Zhang M, Yang X, Zimmerman RJ, Wang Q, Ross MA, Granger JM, Luczak ED, Bedja D, Jiang H, Feng N. Zhang M, et al. Among authors: granger jm. J Mol Cell Cardiol. 2020 Dec;149:73-81. doi: 10.1016/j.yjmcc.2020.09.007. Epub 2020 Sep 22. J Mol Cell Cardiol. 2020. PMID: 32971072 Free PMC article.
Mitochondrial CaMKII causes adverse metabolic reprogramming and dilated cardiomyopathy.
Luczak ED, Wu Y, Granger JM, Joiner MA, Wilson NR, Gupta A, Umapathi P, Murphy KR, Reyes Gaido OE, Sabet A, Corradini E, Tseng WW, Wang Y, Heck AJR, Wei AC, Weiss RG, Anderson ME. Luczak ED, et al. Among authors: granger jm. Nat Commun. 2020 Sep 4;11(1):4416. doi: 10.1038/s41467-020-18165-6. Nat Commun. 2020. PMID: 32887881 Free PMC article.
CaMKII oxidation is a critical performance/disease trade-off acquired at the dawn of vertebrate evolution.
Wang Q, Hernández-Ochoa EO, Viswanathan MC, Blum ID, Do DC, Granger JM, Murphy KR, Wei AC, Aja S, Liu N, Antonescu CM, Florea LD, Talbot CC Jr, Mohr D, Wagner KR, Regot S, Lovering RM, Gao P, Bianchet MA, Wu MN, Cammarato A, Schneider MF, Bever GS, Anderson ME. Wang Q, et al. Among authors: granger jm. Nat Commun. 2021 May 26;12(1):3175. doi: 10.1038/s41467-021-23549-3. Nat Commun. 2021. PMID: 34039988 Free PMC article.
MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII.
Konstantinidis K, Bezzerides VJ, Lai L, Isbell HM, Wei AC, Wu Y, Viswanathan MC, Blum ID, Granger JM, Heims-Waldron D, Zhang D, Luczak ED, Murphy KR, Lu F, Gratz DH, Manta B, Wang Q, Wang Q, Kolodkin AL, Gladyshev VN, Hund TJ, Pu WT, Wu MN, Cammarato A, Bianchet MA, Shea MA, Levine RL, Anderson ME. Konstantinidis K, et al. Among authors: granger jm. J Clin Invest. 2020 Sep 1;130(9):4663-4678. doi: 10.1172/JCI133181. J Clin Invest. 2020. PMID: 32749237 Free PMC article.
Oxidized CaMKII and O-GlcNAcylation cause increased atrial fibrillation in diabetic mice by distinct mechanisms.
Mesubi OO, Rokita AG, Abrol N, Wu Y, Chen B, Wang Q, Granger JM, Tucker-Bartley A, Luczak ED, Murphy KR, Umapathi P, Banerjee PS, Boronina TN, Cole RN, Maier LS, Wehrens XH, Pomerantz JL, Song LS, Ahima RS, Hart GW, Zachara NE, Anderson ME. Mesubi OO, et al. Among authors: granger jm. J Clin Invest. 2021 Jan 19;131(2):e95747. doi: 10.1172/JCI95747. J Clin Invest. 2021. PMID: 33151911 Free PMC article.
12 results