Granovsky AE - Search Results

1

Potency and mechanism of action of E4021, a type 5 phosphodiesterase isozyme-selective inhibitor, on the photoreceptor phosphodiesterase depend on the state of activation of the enzyme.

D'Amours MR, Granovsky AE, Artemyev NO, Cote RH. D'Amours MR, et al. Among authors: granovsky ae. Mol Pharmacol. 1999 Mar;55(3):508-14. Mol Pharmacol. 1999. PMID: 10051534

2

Mutation in rod PDE6 linked to congenital stationary night blindness impairs the enzyme inhibition by its gamma-subunit.

Muradov KG, Granovsky AE, Artemyev NO. Muradov KG, et al. Among authors: granovsky ae. Biochemistry. 2003 Mar 25;42(11):3305-10. doi: 10.1021/bi027095x. Biochemistry. 2003. PMID: 12641462

3

Identification of the gamma subunit-interacting residues on photoreceptor cGMP phosphodiesterase, PDE6alpha '.

Granovsky AE, Artemyev NO. Granovsky AE, et al. J Biol Chem. 2000 Dec 29;275(52):41258-62. doi: 10.1074/jbc.M008094200. J Biol Chem. 2000. PMID: 11024033 Free article.

4

A conformational switch in the inhibitory gamma-subunit of PDE6 upon enzyme activation by transducin.

Granovsky AE, Artemyev NO. Granovsky AE, et al. Biochemistry. 2001 Nov 6;40(44):13209-15. doi: 10.1021/bi011127j. Biochemistry. 2001. PMID: 11683629

5

Partial reconstitution of photoreceptor cGMP phosphodiesterase characteristics in cGMP phosphodiesterase-5.

Granovsky AE, Artemyev NO. Granovsky AE, et al. J Biol Chem. 2001 Jun 15;276(24):21698-703. doi: 10.1074/jbc.M100626200. Epub 2001 Apr 2. J Biol Chem. 2001. PMID: 11285263 Free article.

6

The gamma subunit of rod cGMP-phosphodiesterase blocks the enzyme catalytic site.

Granovsky AE, Natochin M, Artemyev NO. Granovsky AE, et al. J Biol Chem. 1997 May 2;272(18):11686-9. doi: 10.1074/jbc.272.18.11686. J Biol Chem. 1997. PMID: 9115217 Free article.

7

Direct interaction of the inhibitory gamma-subunit of Rod cGMP phosphodiesterase (PDE6) with the PDE6 GAFa domains.

Muradov KG, Granovsky AE, Schey KL, Artemyev NO. Muradov KG, et al. Among authors: granovsky ae. Biochemistry. 2002 Mar 26;41(12):3884-90. doi: 10.1021/bi015935m. Biochemistry. 2002. PMID: 11900530

8

Probing functional interfaces of rod PDE gamma-subunit using scanning fluorescent labeling.

Granovsky AE, McEntaffer R, Artemyev NO. Granovsky AE, et al. Cell Biochem Biophys. 1998;28(2-3):115-33. doi: 10.1007/BF02737808. Cell Biochem Biophys. 1998. PMID: 9515163

9

Probing domain functions of chimeric PDE6alpha'/PDE5 cGMP-phosphodiesterase.

Granovsky AE, Natochin M, McEntaffer RL, Haik TL, Francis SH, Corbin JD, Artemyev NO. Granovsky AE, et al. J Biol Chem. 1998 Sep 18;273(38):24485-90. doi: 10.1074/jbc.273.38.24485. J Biol Chem. 1998. PMID: 9733741 Free article.

10

Inhibition of photoreceptor cGMP phosphodiesterase by its gamma subunit.

Granovsky AE, Muradov KG, Artemyev NO. Granovsky AE, et al. Methods Enzymol. 2000;315:635-46. doi: 10.1016/s0076-6879(00)15872-0. Methods Enzymol. 2000. PMID: 10736731 No abstract available.

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