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NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns.
Massudi H, Grant R, Guillemin GJ, Braidy N. Massudi H, et al. Redox Rep. 2012;17(1):28-46. doi: 10.1179/1351000212Y.0000000001. Redox Rep. 2012. PMID: 22340513 Free PMC article. Review.
Induction of indoleamine 2,3-dioxygenase in primary human macrophages by HIV-1.
Grant RS, Naif H, Thuruthyil SJ, Nasr N, Littlejohn T, Takikawa O, Kapoor V. Grant RS, et al. Redox Rep. 2000;5(2-3):105-7. doi: 10.1179/135100000101535366. Redox Rep. 2000. PMID: 10939284
Inhibition of indoleamine 2,3-dioxygenase activity in IFN-gamma stimulated astroglioma cells decreases intracellular NAD levels.
Grant R, Kapoor V. Grant R, et al. Biochem Pharmacol. 2003 Sep 15;66(6):1033-6. doi: 10.1016/s0006-2952(03)00464-7. Biochem Pharmacol. 2003. PMID: 12963490
Inhibition of IDO activity with either 6-chloro-D-tryptophan (competitive inhibition), or 3-ethoxy beta-carboline (non-competitive inhibition) resulted in a dose-dependent decrease in IDO activity that correlated directly with decreasing [NAD] (R(2)=0.92 and 0.81, respecti …
Inhibition of IDO activity with either 6-chloro-D-tryptophan (competitive inhibition), or 3-ethoxy beta-carboline (non-competitive inhibitio …
Membrane permeability of redox active metal chelators: an important element in reducing hydroxyl radical induced NAD+ depletion in neuronal cells.
Jayasena T, Grant RS, Keerthisinghe N, Solaja I, Smythe GA. Jayasena T, et al. Neurosci Res. 2007 Mar;57(3):454-61. doi: 10.1016/j.neures.2006.12.004. Epub 2007 Jan 8. Neurosci Res. 2007. PMID: 17210195
Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons.
Braidy N, Grant R, Adams S, Brew BJ, Guillemin GJ. Braidy N, et al. Neurotox Res. 2009 Jul;16(1):77-86. doi: 10.1007/s12640-009-9051-z. Epub 2009 Apr 18. Neurotox Res. 2009. PMID: 19526301
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