Grant RA - Search Results

1

Design and selection of novel Cys2His2 zinc finger proteins.

Pabo CO, Peisach E, Grant RA. Pabo CO, et al. Among authors: grant ra. Annu Rev Biochem. 2001;70:313-40. doi: 10.1146/annurev.biochem.70.1.313. Annu Rev Biochem. 2001. PMID: 11395410 Review.

2

Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA.

Wang BS, Grant RA, Pabo CO. Wang BS, et al. Among authors: grant ra. Nat Struct Biol. 2001 Jul;8(7):589-93. doi: 10.1038/89617. Nat Struct Biol. 2001. PMID: 11427887

3

Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes.

Wolfe SA, Grant RA, Elrod-Erickson M, Pabo CO. Wolfe SA, et al. Among authors: grant ra. Structure. 2001 Aug;9(8):717-23. doi: 10.1016/s0969-2126(01)00632-3. Structure. 2001. PMID: 11587646 Free article.

4

Exploring the role of glutamine 50 in the homeodomain-DNA interface: crystal structure of engrailed (Gln50 --> ala) complex at 2.0 A.

Grant RA, Rould MA, Klemm JD, Pabo CO. Grant RA, et al. Biochemistry. 2000 Jul 18;39(28):8187-92. doi: 10.1021/bi000071a. Biochemistry. 2000. PMID: 10889025

5

The crystal structure of Dps, a ferritin homolog that binds and protects DNA.

Grant RA, Filman DJ, Finkel SE, Kolter R, Hogle JM. Grant RA, et al. Nat Struct Biol. 1998 Apr;5(4):294-303. doi: 10.1038/nsb0498-294. Nat Struct Biol. 1998. PMID: 9546221

6

Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.

Grant RA, Hiremath CN, Filman DJ, Syed R, Andries K, Hogle JM. Grant RA, et al. Curr Biol. 1994 Sep 1;4(9):784-97. doi: 10.1016/s0960-9822(00)00176-7. Curr Biol. 1994. PMID: 7820548

7

The immune-evasive proline-283 substitution in influenza nucleoprotein increases aggregation propensity without altering the native structure.

Yoon J, Zhang YM, Her C, Grant RA, Ponomarenko AI, Ackermann BE, Hui T, Lin YS, Debelouchina GT, Shoulders MD. Yoon J, et al. Among authors: grant ra. Sci Adv. 2024 Apr 19;10(16):eadl6144. doi: 10.1126/sciadv.adl6144. Epub 2024 Apr 19. Sci Adv. 2024. PMID: 38640233 Free PMC article.

8

Prolonged exposure to lung-derived cytokines is associated with activation of microglia in patients with COVID-19.

Grant RA, Poor TA, Sichizya L, Diaz E, Bailey JI, Soni S, Senkow KJ, Pérez-Leonor XG, Abdala-Valencia H, Lu Z, Donnelly HK, Simons LM, Ozer EA, Tighe RM, Lomasney JW, Wunderink RG, Singer BD, Misharin AV, Budinger GRS; Northwestern University Successful Clinical Response In Pneumonia Therapy (NU SCRIPT) Investigators. Grant RA, et al. JCI Insight. 2024 Mar 19;9(8):e178859. doi: 10.1172/jci.insight.178859. JCI Insight. 2024. PMID: 38502186 Free article.

9

A distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia.

Markov NS, Ren Z, Senkow KJ, Grant RA, Gao CA, Malsin ES, Sichizya L, Kihshen H, Helmin KA, Jovisic M, Arnold JM, Pérez-Leonor XG, Abdala-Valencia H, Swaminathan S, Nwaezeapu J, Kang M, Rasmussen L, Ozer EA, Lorenzo-Redondo R, Hultquist JF, Simons LM, Rios-Guzman E, Misharin AV, Wunderink RG, Budinger GRS, Singer BD, Morales-Nebreda L; NU SCRIPT Study Investigators. Markov NS, et al. Among authors: grant ra. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571479. doi: 10.1101/2023.12.13.571479. bioRxiv. 2023. PMID: 38168346 Free PMC article. Preprint.

10

The Immune-Evasive Proline 283 Substitution in Influenza Nucleoprotein Increases Aggregation Propensity Without Altering the Native Structure.

Yoon J, Zhang YM, Her C, Grant RA, Ponomarenko AM, Ackermann BE, Debelouchina GT, Shoulders MD. Yoon J, et al. Among authors: grant ra. bioRxiv [Preprint]. 2023 Sep 12:2023.09.08.556894. doi: 10.1101/2023.09.08.556894. bioRxiv. 2023. PMID: 37745335 Free PMC article. Preprint.

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