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Next generation intra- and transdermal therapeutic systems: using non- and minimally-invasive technologies to increase drug delivery into and across the skin.
Gratieri T, Alberti I, Lapteva M, Kalia YN. Gratieri T, et al. Eur J Pharm Sci. 2013 Dec 18;50(5):609-22. doi: 10.1016/j.ejps.2013.03.019. Epub 2013 Apr 6. Eur J Pharm Sci. 2013. PMID: 23567467 Review.
Doxorubicin skin penetration from monoolein-containing propylene glycol formulations.
Herai H, Gratieri T, Thomazine JA, Bentley MV, Lopez RF. Herai H, et al. Among authors: gratieri t. Int J Pharm. 2007 Feb 1;329(1-2):88-93. doi: 10.1016/j.ijpharm.2006.08.021. Epub 2006 Aug 24. Int J Pharm. 2007. PMID: 17027205
The effects of pH and ionic strength on topical delivery of a negatively charged porphyrin (TPPS4).
Gelfuso GM, Figueiredo FV, Gratieri T, Lopez RF. Gelfuso GM, et al. Among authors: gratieri t. J Pharm Sci. 2008 Oct;97(10):4249-57. doi: 10.1002/jps.21295. J Pharm Sci. 2008. PMID: 18240285
A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery.
Gratieri T, Gelfuso GM, Rocha EM, Sarmento VH, de Freitas O, Lopez RF. Gratieri T, et al. Eur J Pharm Biopharm. 2010 Jun;75(2):186-93. doi: 10.1016/j.ejpb.2010.02.011. Epub 2010 Feb 25. Eur J Pharm Biopharm. 2010. PMID: 20188828 Clinical Trial.
The influence of positive or negative charges in the passive and iontophoretic skin penetration of porphyrins used in photodynamic therapy.
Gelfuso GM, Gratieri T, Souza JG, Thomazine JA, Lopez RF. Gelfuso GM, et al. Among authors: gratieri t. Eur J Pharm Biopharm. 2011 Feb;77(2):249-56. doi: 10.1016/j.ejpb.2010.11.018. Epub 2010 Nov 29. Eur J Pharm Biopharm. 2011. PMID: 21118720
Non-invasive iontophoretic delivery of peptides and proteins across the skin.
Gratieri T, Kalaria D, Kalia YN. Gratieri T, et al. Expert Opin Drug Deliv. 2011 May;8(5):645-63. doi: 10.1517/17425247.2011.566265. Epub 2011 Mar 24. Expert Opin Drug Deliv. 2011. PMID: 21428867 Review.
Enhancing and sustaining the topical ocular delivery of fluconazole using chitosan solution and poloxamer/chitosan in situ forming gel.
Gratieri T, Gelfuso GM, de Freitas O, Rocha EM, Lopez RF. Gratieri T, et al. Eur J Pharm Biopharm. 2011 Oct;79(2):320-7. doi: 10.1016/j.ejpb.2011.05.006. Epub 2011 May 27. Eur J Pharm Biopharm. 2011. PMID: 21641994
Chitosan microparticles for sustaining the topical delivery of minoxidil sulphate.
Gelfuso GM, Gratieri T, Simão PS, de Freitas LA, Lopez RF. Gelfuso GM, et al. Among authors: gratieri t. J Microencapsul. 2011;28(7):650-8. doi: 10.3109/02652048.2011.604435. Epub 2011 Aug 9. J Microencapsul. 2011. PMID: 21824068
Mathematical models to describe iontophoretic transport in vitro and in vivo and the effect of current application on the skin barrier.
Gratieri T, Kalia YN. Gratieri T, et al. Adv Drug Deliv Rev. 2013 Feb;65(2):315-29. doi: 10.1016/j.addr.2012.04.012. Epub 2012 May 22. Adv Drug Deliv Rev. 2013. PMID: 22626977 Review.
Iontophoresis-targeted, follicular delivery of minoxidil sulfate for the treatment of alopecia.
Gelfuso GM, Gratieri T, Delgado-Charro MB, Guy RH, Vianna Lopez RF. Gelfuso GM, et al. Among authors: gratieri t. J Pharm Sci. 2013 May;102(5):1488-94. doi: 10.1002/jps.23485. Epub 2013 Feb 28. J Pharm Sci. 2013. PMID: 23450524
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