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Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia.
O'Brien SG, Guilhot F, Larson RA, Gathmann I, Baccarani M, Cervantes F, Cornelissen JJ, Fischer T, Hochhaus A, Hughes T, Lechner K, Nielsen JL, Rousselot P, Reiffers J, Saglio G, Shepherd J, Simonsson B, Gratwohl A, Goldman JM, Kantarjian H, Taylor K, Verhoef G, Bolton AE, Capdeville R, Druker BJ; IRIS Investigators. O'Brien SG, et al. Among authors: Gratwohl A. N Engl J Med. 2003 Mar 13;348(11):994-1004. doi: 10.1056/NEJMoa022457. N Engl J Med. 2003. PMID: 12637609 Clinical Trial.
Dose-finding study of valspodar (PSC 833) with daunorubicin and cytarabine to reverse multidrug resistance in elderly patients with previously untreated acute myeloid leukemia.
Sonneveld P, Burnett A, Vossebeld P, Ben-Am M, Rosenkranz G, Pfister C, Verhoef G, Dekker A, Ossenkoppele G, Ferrant C, Yin L, Gratwohl A, Kovacsovics T, Vellenga E, Capdeville R, Löwenberg B. Sonneveld P, et al. Among authors: Gratwohl A. Hematol J. 2000;1(6):411-21. doi: 10.1038/sj.thj.6200050. Hematol J. 2000. PMID: 11920222 Clinical Trial.
Cytogenetic response to prior treatment with interferon-alpha is predictive for survival after allogeneic hematopoietic stem cell transplantation in chronic myeloid leukemia.
Maywald O, Pfirrmann M, Berger U, Breitscheidel L, Gratwohl A, Kolb HJ, Beelen DW, Tobler A, Metzgeroth G, Gnad SU, Hochhaus A, Hasford J, Hehlmann R, Reiter A; German CML Study Group; Swiss Group of Clinical Cancer Research. Maywald O, et al. Among authors: Gratwohl A. Leukemia. 2006 Mar;20(3):477-84. doi: 10.1038/sj.leu.2404100. Leukemia. 2006. PMID: 16453005
Chemotherapy only compared to chemotherapy followed by transplantation in high risk myelodysplastic syndrome and secondary acute myeloid leukemia; two parallel studies adjusted for various prognostic factors.
Oosterveld M, Muus P, Suciu S, Koller C, Verhoef G, Labar B, Wijermans P, Aul C, Fière D, Selleslag D, Willemze R, Gratwohl A, Ferrant A, Mandelli F, Cortes J, de Witte T, Estey E; EORTC, EBMT, SAKK, GIMEMA Leukemia Groups and the MD Anderson Cancer Center. Oosterveld M, et al. Among authors: Gratwohl A. Leukemia. 2002 Sep;16(9):1615-21. doi: 10.1038/sj.leu.2402591. Leukemia. 2002. PMID: 12200672 Clinical Trial.
Post-remission therapy of adult acute myeloid leukaemia: one cycle of high-dose versus standard-dose cytarabine. Leukaemia Project Group of the Swiss Group for Clinical Cancer Research (SAKK).
Fopp M, Fey MF, Bacchi M, Cavalli F, Gmuer J, Jacky E, Schmid L, Tichelli A, Tobler A, Tschopp L, Von Fliedner V, Gratwohl A. Fopp M, et al. Among authors: Gratwohl A. Ann Oncol. 1997 Mar;8(3):251-7. doi: 10.1023/a:1008267904952. Ann Oncol. 1997. PMID: 9137794 Clinical Trial.
Prophylactic platelet transfusions in acute myeloid leukemia.
Gratwohl A, Tichelli A. Gratwohl A, et al. N Engl J Med. 1998 May 14;338(20):1468; author reply 1469-70. doi: 10.1056/NEJM199805143382014. N Engl J Med. 1998. PMID: 9583978 No abstract available.
Concomitant hairy cell and acute myeloid leukemia.
Rimner T, Went P, Tichelli A, Gratwohl A. Rimner T, et al. Among authors: Gratwohl A. Eur J Haematol. 2006 Jan;76(1):86-8. doi: 10.1111/j.0902-4441.0000.t01-1-EJH2356.x. Eur J Haematol. 2006. PMID: 16343277
Long-term outcome of patients with newly diagnosed chronic myeloid leukemia: a randomized comparison of stem cell transplantation with drug treatment.
Gratwohl A, Pfirrmann M, Zander A, Kröger N, Beelen D, Novotny J, Nerl C, Scheid C, Spiekermann K, Mayer J, Sayer HG, Falge C, Bunjes D, Döhner H, Ganser A, Schmidt-Wolf I, Schwerdtfeger R, Baurmann H, Kuse R, Schmitz N, Wehmeier A, Fischer JT, Ho AD, Wilhelm M, Goebeler ME, Lindemann HW, Bormann M, Hertenstein B, Schlimok G, Baerlocher GM, Aul C, Pfreundschuh M, Fabian M, Staib P, Edinger M, Schatz M, Fauser A, Arnold R, Kindler T, Wulf G, Rosselet A, Hellmann A, Schäfer E, Prümmer O, Schenk M, Hasford J, Heimpel H, Hossfeld DK, Kolb HJ, Büsche G, Haferlach C, Schnittger S, Müller MC, Reiter A, Berger U, Saußele S, Hochhaus A, Hehlmann R; SAKK; German CML Study Group. Gratwohl A, et al. Leukemia. 2016 Mar;30(3):562-9. doi: 10.1038/leu.2015.281. Epub 2015 Oct 14. Leukemia. 2016. PMID: 26464170 Free PMC article. Clinical Trial.
The effect of prior exposure to imatinib on transplant-related mortality.
Deininger M, Schleuning M, Greinix H, Sayer HG, Fischer T, Martinez J, Maziarz R, Olavarria E, Verdonck L, Schaefer K, Boqué C, Faber E, Nagler A, Pogliani E, Russell N, Volin L, Schanz U, Doelken G, Kiehl M, Fauser A, Druker B, Sureda A, Iacobelli S, Brand R, Krahl R, Lange T, Hochhaus A, Gratwohl A, Kolb H, Niederwieser D; European Blood and Marrow Transplantation Group. Deininger M, et al. Among authors: Gratwohl A. Haematologica. 2006 Apr;91(4):452-9. Haematologica. 2006. PMID: 16585011
Evolving concepts in the management of chronic myeloid leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet.
Baccarani M, Saglio G, Goldman J, Hochhaus A, Simonsson B, Appelbaum F, Apperley J, Cervantes F, Cortes J, Deininger M, Gratwohl A, Guilhot F, Horowitz M, Hughes T, Kantarjian H, Larson R, Niederwieser D, Silver R, Hehlmann R; European LeukemiaNet. Baccarani M, et al. Among authors: Gratwohl A. Blood. 2006 Sep 15;108(6):1809-20. doi: 10.1182/blood-2006-02-005686. Epub 2006 May 18. Blood. 2006. PMID: 16709930 Review.
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