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Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.
Nagel D, Spranger S, Vincendeau M, Grau M, Raffegerst S, Kloo B, Hlahla D, Neuenschwander M, Peter von Kries J, Hadian K, Dörken B, Lenz P, Lenz G, Schendel DJ, Krappmann D. Nagel D, et al. Among authors: grau m. Cancer Cell. 2012 Dec 11;22(6):825-37. doi: 10.1016/j.ccr.2012.11.002. Cancer Cell. 2012. PMID: 23238017 Free article.
The use of microarray technologies in mantle cell lymphoma.
Ratsch BA, Grau M, Dörken B, Lenz P, Lenz G. Ratsch BA, et al. Among authors: grau m. Semin Hematol. 2011 Jul;48(3):166-71. doi: 10.1053/j.seminhematol.2011.03.007. Semin Hematol. 2011. PMID: 21782058 Review.
Malt1-dependent RelB cleavage promotes canonical NF-kappaB activation in lymphocytes and lymphoma cell lines.
Hailfinger S, Nogai H, Pelzer C, Jaworski M, Cabalzar K, Charton JE, Guzzardi M, Décaillet C, Grau M, Dörken B, Lenz P, Lenz G, Thome M. Hailfinger S, et al. Among authors: grau m. Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14596-601. doi: 10.1073/pnas.1105020108. Epub 2011 Aug 22. Proc Natl Acad Sci U S A. 2011. PMID: 21873235 Free PMC article.
MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma.
Wenzel SS, Grau M, Mavis C, Hailfinger S, Wolf A, Madle H, Deeb G, Dörken B, Thome M, Lenz P, Dirnhofer S, Hernandez-Ilizaliturri FJ, Tzankov A, Lenz G. Wenzel SS, et al. Among authors: grau m. Leukemia. 2013 Jun;27(6):1381-90. doi: 10.1038/leu.2012.367. Epub 2012 Dec 21. Leukemia. 2013. PMID: 23257783
PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma.
Pfeifer M, Grau M, Lenze D, Wenzel SS, Wolf A, Wollert-Wulf B, Dietze K, Nogai H, Storek B, Madle H, Dörken B, Janz M, Dirnhofer S, Lenz P, Hummel M, Tzankov A, Lenz G. Pfeifer M, et al. Among authors: grau m. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12420-5. doi: 10.1073/pnas.1305656110. Epub 2013 Jul 9. Proc Natl Acad Sci U S A. 2013. PMID: 23840064 Free PMC article.
IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL.
Nogai H, Wenzel SS, Hailfinger S, Grau M, Kaergel E, Seitz V, Wollert-Wulf B, Pfeifer M, Wolf A, Frick M, Dietze K, Madle H, Tzankov A, Hummel M, Dörken B, Scheidereit C, Janz M, Lenz P, Thome M, Lenz G. Nogai H, et al. Among authors: grau m. Blood. 2013 Sep 26;122(13):2242-50. doi: 10.1182/blood-2013-06-508028. Epub 2013 Jul 18. Blood. 2013. PMID: 23869088 Free article.
Gene expression profiling of peripheral blood mononuclear cells during treatment with a gene-modified allogeneic tumor cell vaccine in advanced renal cell cancer: tumor-induced immunosuppression and a possible role for NF-κB.
Flörcken A, Grau M, Wolf A, Weilemann A, Kopp J, Dörken B, Blankenstein T, Pezzutto A, Lenz P, Lenz G, Westermann J. Flörcken A, et al. Among authors: grau m. Int J Cancer. 2015 Apr 15;136(8):1814-26. doi: 10.1002/ijc.29230. Epub 2014 Sep 30. Int J Cancer. 2015. PMID: 25242680 Free article.
Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B-cell activation and proliferation.
Heinig K, Gätjen M, Grau M, Stache V, Anagnostopoulos I, Gerlach K, Niesner RA, Cseresnyes Z, Hauser AE, Lenz P, Hehlgans T, Brink R, Westermann J, Dörken B, Lipp M, Lenz G, Rehm A, Höpken UE. Heinig K, et al. Among authors: grau m. Cancer Discov. 2014 Dec;4(12):1448-65. doi: 10.1158/2159-8290.CD-14-0096. Epub 2014 Sep 24. Cancer Discov. 2014. PMID: 25252690
462 results