Graupera M - Search Results

1

PIK3CA mutations in vascular malformations.

Castillo SD, Baselga E, Graupera M. Castillo SD, et al. Among authors: graupera m. Curr Opin Hematol. 2019 May;26(3):170-178. doi: 10.1097/MOH.0000000000000496. Curr Opin Hematol. 2019. PMID: 30855339 Review.

2

Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.

Soler A, Serra H, Pearce W, Angulo A, Guillermet-Guibert J, Friedman LS, Viñals F, Gerhardt H, Casanovas O, Graupera M, Vanhaesebroeck B. Soler A, et al. Among authors: graupera m. J Exp Med. 2013 Sep 23;210(10):1937-45. doi: 10.1084/jem.20121571. Epub 2013 Sep 16. J Exp Med. 2013. PMID: 24043760 Free PMC article.

3

Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.

Castillo SD, Tzouanacou E, Zaw-Thin M, Berenjeno IM, Parker VE, Chivite I, Milà-Guasch M, Pearce W, Solomon I, Angulo-Urarte A, Figueiredo AM, Dewhurst RE, Knox RG, Clark GR, Scudamore CL, Badar A, Kalber TL, Foster J, Stuckey DJ, David AL, Phillips WA, Lythgoe MF, Wilson V, Semple RK, Sebire NJ, Kinsler VA, Graupera M, Vanhaesebroeck B. Castillo SD, et al. Among authors: graupera m. Sci Transl Med. 2016 Mar 30;8(332):332ra43. doi: 10.1126/scitranslmed.aad9982. Sci Transl Med. 2016. PMID: 27030595 Free PMC article.

4

Therapeutic Benefit of Selective Inhibition of p110α PI3-Kinase in Pancreatic Neuroendocrine Tumors.

Soler A, Figueiredo AM, Castel P, Martin L, Monelli E, Angulo-Urarte A, Milà-Guasch M, Viñals F, Baselga J, Casanovas O, Graupera M. Soler A, et al. Among authors: graupera m. Clin Cancer Res. 2016 Dec 1;22(23):5805-5817. doi: 10.1158/1078-0432.CCR-15-3051. Epub 2016 May 25. Clin Cancer Res. 2016. PMID: 27225693 Free PMC article.

5

The TGFβ pathway stimulates ovarian cancer cell proliferation by increasing IGF1R levels.

Alsina-Sanchis E, Figueras A, Lahiguera Á, Vidal A, Casanovas O, Graupera M, Villanueva A, Viñals F. Alsina-Sanchis E, et al. Among authors: graupera m. Int J Cancer. 2016 Oct 15;139(8):1894-903. doi: 10.1002/ijc.30233. Epub 2016 Jun 25. Int J Cancer. 2016. PMID: 27299695

6

PI3K at the crossroads of tumor angiogenesis signaling pathways.

Soler A, Angulo-Urarte A, Graupera M. Soler A, et al. Among authors: graupera m. Mol Cell Oncol. 2015 Feb 26;2(2):e975624. doi: 10.4161/23723556.2014.975624. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2015. PMID: 27308431 Free PMC article. Review.

7

Resistance to Targeted Therapies in Renal Cancer: The Importance of Changing the Mechanism of Action.

Duran I, Lambea J, Maroto P, González-Larriba JL, Flores L, Granados-Principal S, Graupera M, Sáez B, Vivancos A, Casanovas O. Duran I, et al. Among authors: graupera m. Target Oncol. 2017 Feb;12(1):19-35. doi: 10.1007/s11523-016-0463-4. Target Oncol. 2017. PMID: 27844272 Review.

8

PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia.

Ola R, Dubrac A, Han J, Zhang F, Fang JS, Larrivée B, Lee M, Urarte AA, Kraehling JR, Genet G, Hirschi KK, Sessa WC, Canals FV, Graupera M, Yan M, Young LH, Oh PS, Eichmann A. Ola R, et al. Among authors: graupera m. Nat Commun. 2016 Nov 29;7:13650. doi: 10.1038/ncomms13650. Nat Commun. 2016. PMID: 27897192 Free PMC article.

9

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.

Berenjeno IM, Piñeiro R, Castillo SD, Pearce W, McGranahan N, Dewhurst SM, Meniel V, Birkbak NJ, Lau E, Sansregret L, Morelli D, Kanu N, Srinivas S, Graupera M, Parker VER, Montgomery KG, Moniz LS, Scudamore CL, Phillips WA, Semple RK, Clarke A, Swanton C, Vanhaesebroeck B. Berenjeno IM, et al. Among authors: graupera m. Nat Commun. 2017 Nov 24;8(1):1773. doi: 10.1038/s41467-017-02002-4. Nat Commun. 2017. PMID: 29170395 Free PMC article.

10

ALK1 Loss Results in Vascular Hyperplasia in Mice and Humans Through PI3K Activation.

Alsina-Sanchís E, García-Ibáñez Y, Figueiredo AM, Riera-Domingo C, Figueras A, Matias-Guiu X, Casanovas O, Botella LM, Pujana MA, Riera-Mestre A, Graupera M, Viñals F. Alsina-Sanchís E, et al. Among authors: graupera m. Arterioscler Thromb Vasc Biol. 2018 May;38(5):1216-1229. doi: 10.1161/ATVBAHA.118.310760. Epub 2018 Feb 15. Arterioscler Thromb Vasc Biol. 2018. PMID: 29449337

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