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A combinatorial scaffold approach toward kinase-directed heterocycle libraries.
Ding S, Gray NS, Wu X, Ding Q, Schultz PG. Ding S, et al. J Am Chem Soc. 2002 Feb 27;124(8):1594-6. doi: 10.1021/ja0170302. J Am Chem Soc. 2002. PMID: 11853431
Design of allele-specific protein methyltransferase inhibitors.
Lin Q, Jiang F, Schultz PG, Gray NS. Lin Q, et al. J Am Chem Soc. 2001 Nov 28;123(47):11608-13. doi: 10.1021/ja011423j. J Am Chem Soc. 2001. PMID: 11716715
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.
Gray NS, Wodicka L, Thunnissen AM, Norman TC, Kwon S, Espinoza FH, Morgan DO, Barnes G, LeClerc S, Meijer L, Kim SH, Lockhart DJ, Schultz PG. Gray NS, et al. Science. 1998 Jul 24;281(5376):533-8. doi: 10.1126/science.281.5376.533. Science. 1998. PMID: 9677190
Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors.
Chang YT, Gray NS, Rosania GR, Sutherlin DP, Kwon S, Norman TC, Sarohia R, Leost M, Meijer L, Schultz PG. Chang YT, et al. Chem Biol. 1999 Jun;6(6):361-75. doi: 10.1016/S1074-5521(99)80048-9. Chem Biol. 1999. PMID: 10375538
Combinatorial libraries and biological discovery.
Gray NS. Gray NS. Curr Opin Neurobiol. 2001 Oct;11(5):608-14. doi: 10.1016/s0959-4388(00)00257-9. Curr Opin Neurobiol. 2001. PMID: 11595496 Review.
Synthetic small molecules that control stem cell fate.
Ding S, Wu TY, Brinker A, Peters EC, Hur W, Gray NS, Schultz PG. Ding S, et al. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7632-7. doi: 10.1073/pnas.0732087100. Epub 2003 Jun 6. Proc Natl Acad Sci U S A. 2003. PMID: 12794184 Free PMC article.
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