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CD4 is active as a signaling molecule on the human monocytic cell line Thp-1.
Graziani-Bowering G, Filion LG, Thibault P, Kozlowski M. Graziani-Bowering G, et al. Exp Cell Res. 2002 Sep 10;279(1):141-52. doi: 10.1006/excr.2002.5581. Exp Cell Res. 2002. PMID: 12213222
Monocyte-derived cytokines in multiple sclerosis.
Filion LG, Graziani-Bowering G, Matusevicius D, Freedman MS. Filion LG, et al. Among authors: graziani bowering g. Clin Exp Immunol. 2003 Feb;131(2):324-34. doi: 10.1046/j.1365-2249.2003.02053.x. Clin Exp Immunol. 2003. PMID: 12562396 Free PMC article.
Down regulation of CD4 expression following isolation and culture of human monocytes.
Graziani-Bowering GM, Filion LG. Graziani-Bowering GM, et al. Clin Diagn Lab Immunol. 2000 Mar;7(2):182-91. doi: 10.1128/cdli.7.2.182-191.2000. Clin Diagn Lab Immunol. 2000. PMID: 10702490 Free PMC article.
Monocyte-derived IL12, CD86 (B7-2) and CD40L expression in relapsing and progressive multiple sclerosis.
Filion LG, Matusevicius D, Graziani-Bowering GM, Kumar A, Freedman MS. Filion LG, et al. Among authors: graziani bowering gm. Clin Immunol. 2003 Feb;106(2):127-38. doi: 10.1016/s1521-6616(02)00028-1. Clin Immunol. 2003. PMID: 12672403
Differential regulation of CXCR4 and CCR5 expression by interleukin (IL)-4 and IL-13 is associated with inhibition of chemotaxis and human immunodeficiency Virus (HIV) type 1 replication but not HIV entry into human monocytes.
Creery D, Weiss W, Graziani-Bowering G, Kumar R, Aziz Z, Angel JB, Kumar A. Creery D, et al. Among authors: graziani bowering g. Viral Immunol. 2006 Summer;19(3):409-23. doi: 10.1089/vim.2006.19.409. Viral Immunol. 2006. PMID: 16987060